BRD-A77299732_Salubrinal_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

29 genes differentially expressed following the BRD-A77299732_Salubrinal_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGR2 anterior gradient 2
ANXA3 annexin A3
ASNS asparagine synthetase (glutamine-hydrolyzing)
BASP1 brain abundant, membrane attached signal protein 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
G0S2 G0/G1 switch 2
HMOX1 heme oxygenase 1
IL1B interleukin 1, beta
IL32 interleukin 32
LCN2 lipocalin 2
MAP7 microtubule-associated protein 7
NDRG1 N-myc downstream regulated 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STEAP1 six transmembrane epithelial antigen of the prostate 1
TFF1 trefoil factor 1
THBS1 thrombospondin 1
TNIP1 TNFAIP3 interacting protein 1

decreased expression

Symbol Name
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
GNAS GNAS complex locus
GPNMB glycoprotein (transmembrane) nmb
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
JCHAIN joining chain of multimeric IgA and IgM