BRD-A75409952_wortmannin_SKB_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

71 genes differentially expressed following the BRD-A75409952_wortmannin_SKB_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMD1 adenosylmethionine decarboxylase 1
APLP2 amyloid beta (A4) precursor-like protein 2
BST2 bone marrow stromal cell antigen 2
BTBD3 BTB (POZ) domain containing 3
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLTB clathrin, light chain B
CPD carboxypeptidase D
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CSRP1 cysteine and glycine-rich protein 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FKBP10 FK506 binding protein 10, 65 kDa
HOXC6 homeobox C6
IFI44L interferon-induced protein 44-like
KRT17 keratin 17, type I
LEPR leptin receptor
LEPROT leptin receptor overlapping transcript
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC17 leucine rich repeat containing 17
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MEIS1 Meis homeobox 1
PCOLCE procollagen C-endopeptidase enhancer
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
SCML1 sex comb on midleg-like 1 (Drosophila)
SRGN serglycin
STX1A syntaxin 1A (brain)
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TMPRSS3 transmembrane protease, serine 3
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b

decreased expression

Symbol Name
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
C3ORF14 chromosome 3 open reading frame 14
CAV1 caveolin 1, caveolae protein, 22kDa
CCND2 cyclin D2
CCR2 chemokine (C-C motif) receptor 2
CD200 CD200 molecule
CD24 CD24 molecule
CD52 CD52 molecule
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
COL11A1 collagen, type XI, alpha 1
CORO1A coronin, actin binding protein, 1A
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FGL2 fibrinogen-like 2
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSPA8 heat shock 70kDa protein 8
IL13RA2 interleukin 13 receptor, alpha 2
ITM2A integral membrane protein 2A
LIPG lipase, endothelial
LMO3 LIM domain only 3 (rhombotin-like 2)
LUM lumican
MTSS1 metastasis suppressor 1
NEBL nebulette
NRCAM neuronal cell adhesion molecule
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PSAP prosaposin
RAB21 RAB21, member RAS oncogene family
RABGAP1L RAB GTPase activating protein 1-like
RGS5 regulator of G-protein signaling 5
RRM2 ribonucleotide reductase M2
S100P S100 calcium binding protein P
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
TCEAL2 transcription elongation factor A (SII)-like 2
TFPI2 tissue factor pathway inhibitor 2
TMEM47 transmembrane protein 47
TYMS thymidylate synthetase
UGDH UDP-glucose 6-dehydrogenase
VCAN versican
XIST X inactive specific transcript (non-protein coding)
ZFPM2 zinc finger protein, FOG family member 2