BRD-A73909368_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

79 genes differentially expressed following the BRD-A73909368_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANPEP alanyl (membrane) aminopeptidase
ANXA11 annexin A11
ANXA4 annexin A4
CAPN2 calpain 2, (m/II) large subunit
CAV2 caveolin 2
CHKB choline kinase beta
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COLEC12 collectin sub-family member 12
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EMP1 epithelial membrane protein 1
FGFR3 fibroblast growth factor receptor 3
KDM5D lysine (K)-specific demethylase 5D
KIAA0226L KIAA0226-like
NTS neurotensin
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RPS4Y1 ribosomal protein S4, Y-linked 1
SEPT10 septin 10
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
TGFBI transforming growth factor, beta-induced, 68kDa
THBS2 thrombospondin 2
TPM2 tropomyosin 2 (beta)
VIM vimentin

decreased expression

Symbol Name
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
BAG5 BCL2-associated athanogene 5
CA12 carbonic anhydrase XII
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDK7 cyclin-dependent kinase 7
CDR2 cerebellar degeneration-related protein 2, 62kDa
CHD7 chromodomain helicase DNA binding protein 7
CRTC3 CREB regulated transcription coactivator 3
DBF4 DBF4 zinc finger
DCLRE1C DNA cross-link repair 1C
DHRS2 dehydrogenase/reductase (SDR family) member 2
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FADD Fas (TNFRSF6)-associated via death domain
FAM102A family with sequence similarity 102, member A
FASTKD5 FAST kinase domains 5
G0S2 G0/G1 switch 2
GATA2 GATA binding protein 2
GCH1 GTP cyclohydrolase 1
GEM GTP binding protein overexpressed in skeletal muscle
HILPDA hypoxia inducible lipid droplet-associated
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HOMER1 homer scaffolding protein 1
HSPB8 heat shock 22kDa protein 8
IER3 immediate early response 3
JMJD6 jumonji domain containing 6
KIF2A kinesin heavy chain member 2A
LPAR2 lysophosphatidic acid receptor 2
MED13 mediator complex subunit 13
MSL2 male-specific lethal 2 homolog (Drosophila)
MTF2 metal response element binding transcription factor 2
NOL11 nucleolar protein 11
PDGFA platelet-derived growth factor alpha polypeptide
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
RHOBTB3 Rho-related BTB domain containing 3
RLF rearranged L-myc fusion
S100P S100 calcium binding protein P
SETD5 SET domain containing 5
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SOBP sine oculis binding protein homolog (Drosophila)
SOX4 SRY (sex determining region Y)-box 4
SOX9 SRY (sex determining region Y)-box 9
STC2 stanniocalcin 2
TBX2 T-box 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TLK2 tousled-like kinase 2
TNPO1 transportin 1
VGLL4 vestigial-like family member 4
XBP1 X-box binding protein 1
ZHX2 zinc fingers and homeoboxes 2
ZNF131 zinc finger protein 131