BRD-A71459254_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-A71459254_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACPP acid phosphatase, prostate
ADAM10 ADAM metallopeptidase domain 10
ALCAM activated leukocyte cell adhesion molecule
ATF3 activating transcription factor 3
BCL6 B-cell CLL/lymphoma 6
CLDN1 claudin 1
CLIC4 chloride intracellular channel 4
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXCL8 chemokine (C-X-C motif) ligand 8
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
FAM46A family with sequence similarity 46, member A
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
HIST1H2BG histone cluster 1, H2bg
HIST1H2BK histone cluster 1, H2bk
IFITM1 interferon induced transmembrane protein 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
LCN2 lipocalin 2
MAP7 microtubule-associated protein 7
MMP9 matrix metallopeptidase 9
NAV3 neuron navigator 3
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PDE4B phosphodiesterase 4B, cAMP-specific
PLAU plasminogen activator, urokinase
PTGDS prostaglandin D2 synthase 21kDa (brain)
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RGS2 regulator of G-protein signaling 2
RPP38 ribonuclease P/MRP 38kDa subunit
SPINT2 serine peptidase inhibitor, Kunitz type, 2
TCF4 transcription factor 4
TGM2 transglutaminase 2
TNS3 tensin 3
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSPAN13 tetraspanin 13
TXNIP thioredoxin interacting protein
UPK1B uroplakin 1B
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
AKAP1 A kinase (PRKA) anchor protein 1
ANPEP alanyl (membrane) aminopeptidase
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX1 brain expressed, X-linked 1
CALD1 caldesmon 1
CD24 CD24 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CFD complement factor D (adipsin)
CSRP1 cysteine and glycine-rich protein 1
DCLK1 doublecortin-like kinase 1
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DPYSL2 dihydropyrimidinase-like 2
EIF5 eukaryotic translation initiation factor 5
FSCN1 fascin actin-bundling protein 1
HRSP12 heat-responsive protein 12
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
JAG1 jagged 1
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
LAPTM4B lysosomal protein transmembrane 4 beta
NFIB nuclear factor I/B
PRUNE2 prune homolog 2 (Drosophila)
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RTN2 reticulon 2
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TXNDC9 thioredoxin domain containing 9