BRD-A71262238_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-A71262238_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADIRF adipogenesis regulatory factor
ANGPT2 angiopoietin 2
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
CAV1 caveolin 1, caveolae protein, 22kDa
CD40 CD40 molecule, TNF receptor superfamily member 5
CHN1 chimerin 1
CLC Charcot-Leyden crystal galectin
COL3A1 collagen, type III, alpha 1
CPA3 carboxypeptidase A3 (mast cell)
CPE carboxypeptidase E
DKK3 dickkopf WNT signaling pathway inhibitor 3
EDNRA endothelin receptor type A
ELANE elastase, neutrophil expressed
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPAS1 endothelial PAS domain protein 1
FAM129A family with sequence similarity 129, member A
FBN2 fibrillin 2
FGFR2 fibroblast growth factor receptor 2
GJA1 gap junction protein, alpha 1, 43kDa
GRB7 growth factor receptor-bound protein 7
IPO13 importin 13
KRT19 keratin 19, type I
LPAR6 lysophosphatidic acid receptor 6
MKNK1 MAP kinase interacting serine/threonine kinase 1
MPO myeloperoxidase
MT1M metallothionein 1M
ORC1 origin recognition complex, subunit 1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PRTN3 proteinase 3
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RGCC regulator of cell cycle
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100A8 S100 calcium binding protein A8
SPARCL1 SPARC-like 1 (hevin)
SPRED2 sprouty-related, EVH1 domain containing 2
TES testin LIM domain protein
TPD52 tumor protein D52
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TRIM2 tripartite motif containing 2
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
AGR2 anterior gradient 2
AKAP7 A kinase (PRKA) anchor protein 7
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
CXCL12 chemokine (C-X-C motif) ligand 12
ECI2 enoyl-CoA delta isomerase 2
IL6ST interleukin 6 signal transducer
NFIB nuclear factor I/B
PNMA1 paraneoplastic Ma antigen 1
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SOAT1 sterol O-acyltransferase 1