BRD-A69815203_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-A69815203_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BAG3 BCL2-associated athanogene 3
CCR2 chemokine (C-C motif) receptor 2
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
COBLL1 cordon-bleu WH2 repeat protein-like 1
CREB3L2 cAMP responsive element binding protein 3-like 2
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DOCK9 dedicator of cytokinesis 9
DUSP1 dual specificity phosphatase 1
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
FADS1 fatty acid desaturase 1
FBN2 fibrillin 2
GARS glycyl-tRNA synthetase
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GLRX glutaredoxin (thioltransferase)
GORASP2 golgi reassembly stacking protein 2, 55kDa
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2BG histone cluster 1, H2bg
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA13 heat shock protein 70kDa family, member 13
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IGHM immunoglobulin heavy constant mu
IGKV4-1 immunoglobulin kappa variable 4-1
IL6ST interleukin 6 signal transducer
INSIG1 insulin induced gene 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
LDLR low density lipoprotein receptor
LRRC59 leucine rich repeat containing 59
MANF mesencephalic astrocyte-derived neurotrophic factor
MSMO1 methylsterol monooxygenase 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
RAD9A RAD9 homolog A (S. pombe)
RNASE6 ribonuclease, RNase A family, k6
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEC24D SEC24 family member D
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SERP1 stress-associated endoplasmic reticulum protein 1
SLC35B1 solute carrier family 35, member B1
SQLE squalene epoxidase
THBS2 thrombospondin 2
TRAM1 translocation associated membrane protein 1
TXNDC9 thioredoxin domain containing 9
UFM1 ubiquitin-fold modifier 1
VCAN versican
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
GPM6B glycoprotein M6B
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MATN2 matrilin 2
MMP9 matrix metallopeptidase 9
PCP4 Purkinje cell protein 4
PLAC8 placenta-specific 8
SPRY2 sprouty homolog 2 (Drosophila)
WT1 Wilms tumor 1