BRD-A69815203_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

90 genes differentially expressed following the BRD-A69815203_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
AQP9 aquaporin 9
ASNS asparagine synthetase (glutamine-hydrolyzing)
BCHE butyrylcholinesterase
CD36 CD36 molecule (thrombospondin receptor)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CKAP4 cytoskeleton-associated protein 4
COL1A1 collagen, type I, alpha 1
COL5A2 collagen, type V, alpha 2
CRABP2 cellular retinoic acid binding protein 2
CSRP2 cysteine and glycine-rich protein 2
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DFNA5 deafness, autosomal dominant 5
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EPRS glutamyl-prolyl-tRNA synthetase
FKBP11 FK506 binding protein 11, 19 kDa
FKBP14 FK506 binding protein 14, 22 kDa
G0S2 G0/G1 switch 2
GARS glycyl-tRNA synthetase
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GNAS GNAS complex locus
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HPSE heparanase
HYOU1 hypoxia up-regulated 1
IL6ST interleukin 6 signal transducer
IPO13 importin 13
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KLF2 Kruppel-like factor 2
LAMB1 laminin, beta 1
LEF1 lymphoid enhancer-binding factor 1
LRRC17 leucine rich repeat containing 17
MAGT1 magnesium transporter 1
MANF mesencephalic astrocyte-derived neurotrophic factor
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MN1 meningioma (disrupted in balanced translocation) 1
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYH10 myosin, heavy chain 10, non-muscle
NID1 nidogen 1
NUCB2 nucleobindin 2
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
RHOQ ras homolog family member Q
SCGB2A2 secretoglobin, family 2A, member 2
SCUBE2 signal peptide, CUB domain, EGF-like 2
SDC2 syndecan 2
SEC24D SEC24 family member D
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
THBS1 thrombospondin 1
THY1 Thy-1 cell surface antigen
TNNT1 troponin T type 1 (skeletal, slow)
VCAN versican
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
C1S complement component 1, s subcomponent
CCDC86 coiled-coil domain containing 86
CCND1 cyclin D1
CLIC4 chloride intracellular channel 4
CLTC clathrin, heavy chain (Hc)
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
KAZN kazrin, periplakin interacting protein
KRT19 keratin 19, type I
KRT7 keratin 7, type II
LAPTM4B lysosomal protein transmembrane 4 beta
MAP7 microtubule-associated protein 7
NOV nephroblastoma overexpressed
NPY neuropeptide Y
PCNA proliferating cell nuclear antigen
PKM pyruvate kinase, muscle
PRR7 proline rich 7 (synaptic)
PTGDS prostaglandin D2 synthase 21kDa (brain)
RNF167 ring finger protein 167
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SEPP1 selenoprotein P, plasma, 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SPRY2 sprouty homolog 2 (Drosophila)
STX1A syntaxin 1A (brain)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TM4SF1 transmembrane 4 L six family member 1
TPD52L1 tumor protein D52-like 1