BRD-A68739437_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

29 genes differentially expressed following the BRD-A68739437_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ALDOC aldolase C, fructose-bisphosphate
ANKRD10 ankyrin repeat domain 10
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
DHCR7 7-dehydrocholesterol reductase
ERBB3 erb-b2 receptor tyrosine kinase 3
GPNMB glycoprotein (transmembrane) nmb
HIST1H1C histone cluster 1, H1c
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP5 insulin-like growth factor binding protein 5
INSIG1 insulin induced gene 1
MT1F metallothionein 1F
NCAM1 neural cell adhesion molecule 1
RAB38 RAB38, member RAS oncogene family
RAB4A RAB4A, member RAS oncogene family
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SQLE squalene epoxidase
STXBP1 syntaxin binding protein 1
TIMP3 TIMP metallopeptidase inhibitor 3
TNS1 tensin 1

decreased expression

Symbol Name
CNPY3 canopy FGF signaling regulator 3
CXCL14 chemokine (C-X-C motif) ligand 14
FOXG1 forkhead box G1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
NME4 NME/NM23 nucleoside diphosphate kinase 4
SPRY2 sprouty homolog 2 (Drosophila)