BRD-A68061604_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-A68061604_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CD9 CD9 molecule
DDIT4 DNA-damage-inducible transcript 4
EBP emopamil binding protein (sterol isomerase)
FOXO3 forkhead box O3
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HSPA1A heat shock 70kDa protein 1A
IL1R1 interleukin 1 receptor, type I
INHBA inhibin, beta A
INSIG1 insulin induced gene 1
KLHL24 kelch-like family member 24
LPIN1 lipin 1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MGP matrix Gla protein
NUPR1 nuclear protein, transcriptional regulator, 1
RHOQ ras homolog family member Q
RNF13 ring finger protein 13
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SQLE squalene epoxidase
SQSTM1 sequestosome 1
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
CA2 carbonic anhydrase II
CD40 CD40 molecule, TNF receptor superfamily member 5
CPE carboxypeptidase E
DLD dihydrolipoamide dehydrogenase
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GAL galanin/GMAP prepropeptide
GATA2 GATA binding protein 2
GJA1 gap junction protein, alpha 1, 43kDa
HIST1H2BD histone cluster 1, H2bd
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
INTS3 integrator complex subunit 3
MEIS2 Meis homeobox 2
MRPS2 mitochondrial ribosomal protein S2
MTERF3 mitochondrial transcription termination factor 3
NEFH neurofilament, heavy polypeptide
NELL2 NEL-like 2 (chicken)
NLRP2 NLR family, pyrin domain containing 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
P3H2 prolyl 3-hydroxylase 2
PDZD2 PDZ domain containing 2
PFDN4 prefoldin subunit 4
PRDX2 peroxiredoxin 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RGS1 regulator of G-protein signaling 1
SNX7 sorting nexin 7
XIST X inactive specific transcript (non-protein coding)