BRD-A68061604_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-A68061604_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ASNS asparagine synthetase (glutamine-hydrolyzing)
CD58 CD58 molecule
CFD complement factor D (adipsin)
CLIC4 chloride intracellular channel 4
DPYSL2 dihydropyrimidinase-like 2
GARS glycyl-tRNA synthetase
GDF15 growth differentiation factor 15
GLRX glutaredoxin (thioltransferase)
GPR137B G protein-coupled receptor 137B
GUSBP11 glucuronidase, beta pseudogene 11
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IGLV2-23 immunoglobulin lambda variable 2-23
INSIG1 insulin induced gene 1
LXN latexin
MICB MHC class I polypeptide-related sequence B
MUC5B mucin 5B, oligomeric mucus/gel-forming
NEU1 sialidase 1 (lysosomal sialidase)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PHGDH phosphoglycerate dehydrogenase
PYCR1 pyrroline-5-carboxylate reductase 1
RCAN1 regulator of calcineurin 1
SDCBP syndecan binding protein (syntenin)
SLC38A1 solute carrier family 38, member 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TRIB3 tribbles pseudokinase 3
TRIM2 tripartite motif containing 2
VAT1 vesicle amine transport 1

decreased expression

Symbol Name
ASCL1 achaete-scute family bHLH transcription factor 1
BTG3 BTG family, member 3
CADM1 cell adhesion molecule 1
CCND1 cyclin D1
EGFR epidermal growth factor receptor
GJA1 gap junction protein, alpha 1, 43kDa
HAL histidine ammonia-lyase
IGFBP3 insulin-like growth factor binding protein 3
MRPS2 mitochondrial ribosomal protein S2
MSH6 mutS homolog 6
MYO1B myosin IB
PFN2 profilin 2
RBP1 retinol binding protein 1, cellular
ST5 suppression of tumorigenicity 5
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)