BRD-A68009927_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

30 genes differentially expressed following the BRD-A68009927_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
COL6A2 collagen, type VI, alpha 2
CPE carboxypeptidase E
EMP1 epithelial membrane protein 1
FST follistatin
GRB7 growth factor receptor-bound protein 7
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
KIAA0226L KIAA0226-like
MAOA monoamine oxidase A
MDFIC MyoD family inhibitor domain containing
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial
MKNK1 MAP kinase interacting serine/threonine kinase 1
NPTX2 neuronal pentraxin II
PRAME preferentially expressed antigen in melanoma
SCNN1A sodium channel, non voltage gated 1 alpha subunit
UGP2 UDP-glucose pyrophosphorylase 2

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
DDIT4 DNA-damage-inducible transcript 4
FASTKD5 FAST kinase domains 5
GCH1 GTP cyclohydrolase 1
KDM2A lysine (K)-specific demethylase 2A
MMP7 matrix metallopeptidase 7
MYC v-myc avian myelocytomatosis viral oncogene homolog
NOP56 NOP56 ribonucleoprotein
NOTCH2 notch 2
NR2F2 nuclear receptor subfamily 2, group F, member 2
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SMAD3 SMAD family member 3
SMAD7 SMAD family member 7
SRC SRC proto-oncogene, non-receptor tyrosine kinase