BRD-A64290322_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

96 genes differentially expressed following the BRD-A64290322_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ARMCX3 armadillo repeat containing, X-linked 3
ASNS asparagine synthetase (glutamine-hydrolyzing)
BASP1 brain abundant, membrane attached signal protein 1
BCL6 B-cell CLL/lymphoma 6
BLNK B-cell linker
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CANX calnexin
CASP7 caspase 7, apoptosis-related cysteine peptidase
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CHIC2 cysteine-rich hydrophobic domain 2
CLIC4 chloride intracellular channel 4
CLU clusterin
COL4A5 collagen, type IV, alpha 5
CREB3L2 cAMP responsive element binding protein 3-like 2
CREM cAMP responsive element modulator
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DSC2 desmocollin 2
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPN2 epsin 2
EVI2A ecotropic viral integration site 2A
FBN2 fibrillin 2
FKBP14 FK506 binding protein 14, 22 kDa
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GRAMD3 GRAM domain containing 3
GUSBP3 glucuronidase, beta pseudogene 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
MAP7 microtubule-associated protein 7
MB myoglobin
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NUCB2 nucleobindin 2
NUPR1 nuclear protein, transcriptional regulator, 1
PEG3 paternally expressed 3
PERP PERP, TP53 apoptosis effector
PLSCR4 phospholipid scramblase 4
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RAD51C RAD51 paralog C
REEP5 receptor accessory protein 5
SAT1 spermidine/spermine N1-acetyltransferase 1
SEC24D SEC24 family member D
SGPP1 sphingosine-1-phosphate phosphatase 1
SIK1 salt-inducible kinase 1
SSR1 signal sequence receptor, alpha
TFF1 trefoil factor 1
TMED2 transmembrane emp24 domain trafficking protein 2
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TPD52 tumor protein D52
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
TXNIP thioredoxin interacting protein
WIPI1 WD repeat domain, phosphoinositide interacting 1
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
BEX1 brain expressed, X-linked 1
BZW2 basic leucine zipper and W2 domains 2
C1ORF106 chromosome 1 open reading frame 106
C7 complement component 7
CDK4 cyclin-dependent kinase 4
CHRDL1 chordin-like 1
CIAPIN1 cytokine induced apoptosis inhibitor 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
CYTL1 cytokine-like 1
FHL1 four and a half LIM domains 1
GLUL glutamate-ammonia ligase
GPX3 glutathione peroxidase 3
GTSE1 G-2 and S-phase expressed 1
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
IFI27 interferon, alpha-inducible protein 27
LGALS3 lectin, galactoside-binding, soluble, 3
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MSMB microseminoprotein, beta-
MX1 MX dynamin-like GTPase 1
NDC80 NDC80 kinetochore complex component
NDNF neuron-derived neurotrophic factor
NENF neudesin neurotrophic factor
PDZK1 PDZ domain containing 1
PENK proenkephalin
PLK1 polo-like kinase 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SPTBN1 spectrin, beta, non-erythrocytic 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TARBP1 TAR (HIV-1) RNA binding protein 1
TFPI2 tissue factor pathway inhibitor 2
TMEM164 transmembrane protein 164
TOP2A topoisomerase (DNA) II alpha 170kDa
TRIM14 tripartite motif containing 14
TSPAN8 tetraspanin 8
UBE2C ubiquitin-conjugating enzyme E2C