BRD-A64228451_EI-328_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

34 genes differentially expressed following the BRD-A64228451_EI-328_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ATF3 activating transcription factor 3
BLNK B-cell linker
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLU clusterin
CXCL8 chemokine (C-X-C motif) ligand 8
DENND2D DENN/MADD domain containing 2D
EMP1 epithelial membrane protein 1
FOSL1 FOS-like antigen 1
FTH1 ferritin, heavy polypeptide 1
GCLM glutamate-cysteine ligase, modifier subunit
HBB hemoglobin, beta
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
JAG1 jagged 1
NAMPT nicotinamide phosphoribosyltransferase
PROM1 prominin 1
S100A9 S100 calcium binding protein A9
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERTAD2 SERTA domain containing 2
TSKU tsukushi, small leucine rich proteoglycan

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
CENPA centromere protein A
GPSM2 G-protein signaling modulator 2
MFAP5 microfibrillar associated protein 5
NFIB nuclear factor I/B
PLK1 polo-like kinase 1
TACSTD2 tumor-associated calcium signal transducer 2
TOP2A topoisomerase (DNA) II alpha 170kDa
UBE2C ubiquitin-conjugating enzyme E2C