BRD-A63894585_Clobetasol propionate_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

105 genes differentially expressed following the BRD-A63894585_Clobetasol propionate_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AIM1 absent in melanoma 1
BAX BCL2-associated X protein
BIRC3 baculoviral IAP repeat containing 3
CD9 CD9 molecule
CDC42 cell division cycle 42
COL3A1 collagen, type III, alpha 1
DDIT4 DNA-damage-inducible transcript 4
DRAM1 DNA-damage regulated autophagy modulator 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EIF5A eukaryotic translation initiation factor 5A
EZR ezrin
FKBP5 FK506 binding protein 5
FOLR1 folate receptor 1 (adult)
FTH1 ferritin, heavy polypeptide 1
FUCA1 fucosidase, alpha-L- 1, tissue
ICAM1 intercellular adhesion molecule 1
IL32 interleukin 32
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KYNU kynureninase
LDLR low density lipoprotein receptor
LITAF lipopolysaccharide-induced TNF factor
LXN latexin
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
ORC1 origin recognition complex, subunit 1
PLAT plasminogen activator, tissue
PLBD1 phospholipase B domain containing 1
PLD3 phospholipase D family, member 3
PSENEN presenilin enhancer gamma secretase subunit
PTGDS prostaglandin D2 synthase 21kDa (brain)
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDC4 syndecan 4
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SMCO4 single-pass membrane protein with coiled-coil domains 4
TGM2 transglutaminase 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TLE4 transducin-like enhancer of split 4
TLR4 toll-like receptor 4
TMPRSS2 transmembrane protease, serine 2
TSC22D3 TSC22 domain family, member 3
VCAM1 vascular cell adhesion molecule 1
WFDC1 WAP four-disulfide core domain 1
ZBTB16 zinc finger and BTB domain containing 16

decreased expression

Symbol Name
ACOX2 acyl-CoA oxidase 2, branched chain
ADGRG1 adhesion G protein-coupled receptor G1
AHSG alpha-2-HS-glycoprotein
ANGPTL2 angiopoietin-like 2
ARHGAP29 Rho GTPase activating protein 29
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX1 brain expressed, X-linked 1
BPHL biphenyl hydrolase-like (serine hydrolase)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
COL5A2 collagen, type V, alpha 2
CSRP2 cysteine and glycine-rich protein 2
CXCL14 chemokine (C-X-C motif) ligand 14
DCT dopachrome tautomerase
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPHA3 EPH receptor A3
FAM46A family with sequence similarity 46, member A
FST follistatin
GPC3 glypican 3
GPNMB glycoprotein (transmembrane) nmb
GPX3 glutathione peroxidase 3
H2AFV H2A histone family, member V
HCP5 HLA complex P5 (non-protein coding)
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFBP3 insulin-like growth factor binding protein 3
IL1R2 interleukin 1 receptor, type II
JUN jun proto-oncogene
LAMA4 laminin, alpha 4
LAMB1 laminin, beta 1
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MARCKS myristoylated alanine-rich protein kinase C substrate
MARCKSL1 MARCKS-like 1
MOK MOK protein kinase
NAV3 neuron navigator 3
NID1 nidogen 1
NREP neuronal regeneration related protein
NRN1 neuritin 1
OLFML3 olfactomedin-like 3
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDZRN3 PDZ domain containing ring finger 3
PMEL premelanosome protein
PPAP2B phosphatidic acid phosphatase type 2B
PTX3 pentraxin 3, long
RET ret proto-oncogene
S100A7 S100 calcium binding protein A7
SDC1 syndecan 1
SFRP1 secreted frizzled-related protein 1
SPON1 spondin 1, extracellular matrix protein
SRPX sushi-repeat containing protein, X-linked
SSFA2 sperm specific antigen 2
TFF3 trefoil factor 3 (intestinal)
THBS4 thrombospondin 4
TYRP1 tyrosinase-related protein 1
XIST X inactive specific transcript (non-protein coding)