BRD-A63583287_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-A63583287_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
ATF3 activating transcription factor 3
BAG3 BCL2-associated athanogene 3
CADM1 cell adhesion molecule 1
CD163 CD163 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CSRP2 cysteine and glycine-rich protein 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
EIF5A eukaryotic translation initiation factor 5A
FOSL1 FOS-like antigen 1
GAGE3 G antigen 3
GCLM glutamate-cysteine ligase, modifier subunit
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IER5 immediate early response 5
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
JUN jun proto-oncogene
MME membrane metallo-endopeptidase
MT1F metallothionein 1F
MT1M metallothionein 1M
MT1X metallothionein 1X
NQO1 NAD(P)H dehydrogenase, quinone 1
NXF1 nuclear RNA export factor 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
STC2 stanniocalcin 2
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AQP3 aquaporin 3 (Gill blood group)
BMP4 bone morphogenetic protein 4
CTSH cathepsin H
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
HES1 hes family bHLH transcription factor 1
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
MGP matrix Gla protein
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
PLK1 polo-like kinase 1
PPARG peroxisome proliferator-activated receptor gamma
RGS2 regulator of G-protein signaling 2
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
TESC tescalcin
TGM2 transglutaminase 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TSPAN8 tetraspanin 8