BRD-A62336480_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

85 genes differentially expressed following the BRD-A62336480_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
AGR2 anterior gradient 2
AMACR alpha-methylacyl-CoA racemase
ARHGAP29 Rho GTPase activating protein 29
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
CADM1 cell adhesion molecule 1
CCP110 centriolar coiled coil protein 110kDa
CD200 CD200 molecule
CHN2 chimerin 2
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLIC4 chloride intracellular channel 4
CXCL9 chemokine (C-X-C motif) ligand 9
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ERBB3 erb-b2 receptor tyrosine kinase 3
ESR1 estrogen receptor 1
FAM134B family with sequence similarity 134, member B
FN1 fibronectin 1
FOXO3 forkhead box O3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXC6 homeobox C6
IL32 interleukin 32
IL6ST interleukin 6 signal transducer
INSIG1 insulin induced gene 1
LEF1 lymphoid enhancer-binding factor 1
LIMCH1 LIM and calponin homology domains 1
MAP7 microtubule-associated protein 7
MSMO1 methylsterol monooxygenase 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NNMT nicotinamide N-methyltransferase
NR2F2 nuclear receptor subfamily 2, group F, member 2
NUPR1 nuclear protein, transcriptional regulator, 1
OSBPL10 oxysterol binding protein-like 10
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
RGS13 regulator of G-protein signaling 13
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SGK1 serum/glucocorticoid regulated kinase 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SORBS2 sorbin and SH3 domain containing 2
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SYBU syntabulin (syntaxin-interacting)
TFF3 trefoil factor 3 (intestinal)
TMEM47 transmembrane protein 47
TRIB3 tribbles pseudokinase 3
TSC22D3 TSC22 domain family, member 3
TUFT1 tuftelin 1
TUSC3 tumor suppressor candidate 3
VCAN versican

decreased expression

Symbol Name
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AKAP12 A kinase (PRKA) anchor protein 12
AZU1 azurocidin 1
CD44 CD44 molecule (Indian blood group)
CDC20 cell division cycle 20
CTSZ cathepsin Z
CYBA cytochrome b-245, alpha polypeptide
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFI6 interferon, alpha-inducible protein 6
JMJD6 jumonji domain containing 6
KRT14 keratin 14, type I
KRT5 keratin 5, type II
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MDK midkine (neurite growth-promoting factor 2)
MMP12 matrix metallopeptidase 12
NME4 NME/NM23 nucleoside diphosphate kinase 4
NQO1 NAD(P)H dehydrogenase, quinone 1
OXTR oxytocin receptor
PI3 peptidase inhibitor 3, skin-derived
PLIN2 perilipin 2
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
S100A6 S100 calcium binding protein A6
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)