BRD-A61470182_N-FORMYLMETHIONYLALANINE_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

131 genes differentially expressed following the BRD-A61470182_N-FORMYLMETHIONYLALANINE_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALOX5AP arachidonate 5-lipoxygenase-activating protein
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGAP29 Rho GTPase activating protein 29
ARL4C ADP-ribosylation factor-like 4C
ASS1 argininosuccinate synthase 1
AUTS2 autism susceptibility candidate 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BSG basigin (Ok blood group)
CA2 carbonic anhydrase II
CD24 CD24 molecule
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CKB creatine kinase, brain
CNN3 calponin 3, acidic
COL5A2 collagen, type V, alpha 2
CPB1 carboxypeptidase B1 (tissue)
CRABP2 cellular retinoic acid binding protein 2
CXCL10 chemokine (C-X-C motif) ligand 10
CXCR4 chemokine (C-X-C motif) receptor 4
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DUSP1 dual specificity phosphatase 1
EGLN3 egl-9 family hypoxia-inducible factor 3
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GAL galanin/GMAP prepropeptide
GJA1 gap junction protein, alpha 1, 43kDa
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GRB7 growth factor receptor-bound protein 7
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL32 interleukin 32
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
JUP junction plakoglobin
KRT18 keratin 18, type I
LAMP3 lysosomal-associated membrane protein 3
LDOC1 leucine zipper, down-regulated in cancer 1
LIMCH1 LIM and calponin homology domains 1
LPL lipoprotein lipase
MEST mesoderm specific transcript
MOSPD1 motile sperm domain containing 1
NEFH neurofilament, heavy polypeptide
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NMU neuromedin U
NNMT nicotinamide N-methyltransferase
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NR2F1 nuclear receptor subfamily 2, group F, member 1
P3H2 prolyl 3-hydroxylase 2
PCLO piccolo presynaptic cytomatrix protein
PDZD2 PDZ domain containing 2
PEG10 paternally expressed 10
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PMM2 phosphomannomutase 2
PTPRK protein tyrosine phosphatase, receptor type, K
RGCC regulator of cell cycle
RGS1 regulator of G-protein signaling 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SOX11 SRY (sex determining region Y)-box 11
SPON2 spondin 2, extracellular matrix protein
SPRED2 sprouty-related, EVH1 domain containing 2
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
TFPI2 tissue factor pathway inhibitor 2
THY1 Thy-1 cell surface antigen
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRIB2 tribbles pseudokinase 2
TRIB3 tribbles pseudokinase 3
VEGFA vascular endothelial growth factor A
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
WT1 Wilms tumor 1
ZEB1 zinc finger E-box binding homeobox 1
ZFP36 ZFP36 ring finger protein
ZFPM2 zinc finger protein, FOG family member 2

decreased expression

Symbol Name
AKAP7 A kinase (PRKA) anchor protein 7
ALCAM activated leukocyte cell adhesion molecule
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
APOD apolipoprotein D
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
CD59 CD59 molecule, complement regulatory protein
CFH complement factor H
CNN1 calponin 1, basic, smooth muscle
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYTL1 cytokine-like 1
DARS aspartyl-tRNA synthetase
DES desmin
E2F2 E2F transcription factor 2
EPCAM epithelial cell adhesion molecule
ERAP2 endoplasmic reticulum aminopeptidase 2
FBXL12 F-box and leucine-rich repeat protein 12
FOLR1 folate receptor 1 (adult)
GMDS GDP-mannose 4,6-dehydratase
GSN gelsolin
HOOK2 hook microtubule-tethering protein 2
KIF14 kinesin family member 14
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LRP4 low density lipoprotein receptor-related protein 4
MLANA melan-A
MYH11 myosin, heavy chain 11, smooth muscle
OLFM4 olfactomedin 4
PEBP1 phosphatidylethanolamine binding protein 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLN phospholamban
PRSS2 protease, serine, 2 (trypsin 2)
PSCA prostate stem cell antigen
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PURA purine-rich element binding protein A
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RPS11 ribosomal protein S11
S100P S100 calcium binding protein P
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SORBS1 sorbin and SH3 domain containing 1
SPINK1 serine peptidase inhibitor, Kazal type 1
STEAP1 six transmembrane epithelial antigen of the prostate 1
TACC1 transforming, acidic coiled-coil containing protein 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TMEM87A transmembrane protein 87A
TSPAN8 tetraspanin 8