BRD-A61470182_N-FORMYLMETHIONYLALANINE_A375_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

79 genes differentially expressed following the BRD-A61470182_N-FORMYLMETHIONYLALANINE_A375_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRL2 adhesion G protein-coupled receptor L2
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
C1ORF116 chromosome 1 open reading frame 116
CADM1 cell adhesion molecule 1
CCL5 chemokine (C-C motif) ligand 5
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CEMIP cell migration inducing protein, hyaluronan binding
CLDN7 claudin 7
CTNND1 catenin (cadherin-associated protein), delta 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
EPN2 epsin 2
EXT1 exostosin glycosyltransferase 1
FLNB filamin B, beta
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GPATCH8 G patch domain containing 8
HLA-B major histocompatibility complex, class I, B
IGHM immunoglobulin heavy constant mu
KANK1 KN motif and ankyrin repeat domains 1
LAMA4 laminin, alpha 4
LPAR6 lysophosphatidic acid receptor 6
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MALL mal, T-cell differentiation protein-like
MEST mesoderm specific transcript
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PON3 paraoxonase 3
PRUNE2 prune homolog 2 (Drosophila)
RIPK4 receptor-interacting serine-threonine kinase 4
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
S100A8 S100 calcium binding protein A8
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFRP1 secreted frizzled-related protein 1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TCTA T-cell leukemia translocation altered
TM4SF1 transmembrane 4 L six family member 1
TMEM30B transmembrane protein 30B
TMPRSS2 transmembrane protease, serine 2
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
WNT5A wingless-type MMTV integration site family, member 5A
XYLT1 xylosyltransferase I
ZNF274 zinc finger protein 274

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
ANO1 anoctamin 1, calcium activated chloride channel
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CHMP4A charged multivesicular body protein 4A
CHN2 chimerin 2
COL9A3 collagen, type IX, alpha 3
CPVL carboxypeptidase, vitellogenic-like
CSNK1A1 casein kinase 1, alpha 1
CTSB cathepsin B
CYBRD1 cytochrome b reductase 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GRB14 growth factor receptor-bound protein 14
GSTM3 glutathione S-transferase mu 3 (brain)
HAL histidine ammonia-lyase
HSPA1A heat shock 70kDa protein 1A
LHX2 LIM homeobox 2
MARCKSL1 MARCKS-like 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
PBLD phenazine biosynthesis-like protein domain containing
PLA2G16 phospholipase A2, group XVI
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRSS3 protease, serine, 3
PTGDS prostaglandin D2 synthase 21kDa (brain)
REEP1 receptor accessory protein 1
RRAGD Ras-related GTP binding D
SOX9 SRY (sex determining region Y)-box 9
SQRDL sulfide quinone reductase-like (yeast)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THY1 Thy-1 cell surface antigen
TMBIM6 transmembrane BAX inhibitor motif containing 6
UGCG UDP-glucose ceramide glucosyltransferase