BRD-A60784279_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

71 genes differentially expressed following the BRD-A60784279_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CALR calreticulin
CBS cystathionine-beta-synthase
CD24 CD24 molecule
CD9 CD9 molecule
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CKAP4 cytoskeleton-associated protein 4
CLDN3 claudin 3
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DUSP1 dual specificity phosphatase 1
ENAH enabled homolog (Drosophila)
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FASN fatty acid synthase
IGFBP7 insulin-like growth factor binding protein 7
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
INSIG1 insulin induced gene 1
KDM5D lysine (K)-specific demethylase 5D
LDOC1 leucine zipper, down-regulated in cancer 1
LIMCH1 LIM and calponin homology domains 1
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MTA1 metastasis associated 1
PPL periplakin
PRDX2 peroxiredoxin 2
RNF167 ring finger protein 167
S100A9 S100 calcium binding protein A9
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
STX1A syntaxin 1A (brain)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNC tenascin C
VCAN versican
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
AGR2 anterior gradient 2
AKAP12 A kinase (PRKA) anchor protein 12
ANXA1 annexin A1
CD3D CD3d molecule, delta (CD3-TCR complex)
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
ETNK1 ethanolamine kinase 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GALC galactosylceramidase
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPNMB glycoprotein (transmembrane) nmb
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HOXC6 homeobox C6
IFI27 interferon, alpha-inducible protein 27
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ISG15 ISG15 ubiquitin-like modifier
LGALS1 lectin, galactoside-binding, soluble, 1
LYZ lysozyme
MRPS12 mitochondrial ribosomal protein S12
MRPS16 mitochondrial ribosomal protein S16
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYRF myelin regulatory factor
PBLD phenazine biosynthesis-like protein domain containing
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
PRAME preferentially expressed antigen in melanoma
PRDX4 peroxiredoxin 4
PTGDS prostaglandin D2 synthase 21kDa (brain)
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SRPX sushi-repeat containing protein, X-linked
TRAPPC2L trafficking protein particle complex 2-like
TYRP1 tyrosinase-related protein 1
ZNF593 zinc finger protein 593