BRD-A60245366_AS-601245_MDAMB231_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

78 genes differentially expressed following the BRD-A60245366_AS-601245_MDAMB231_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ARPP19 cAMP-regulated phosphoprotein, 19kDa
C1ORF115 chromosome 1 open reading frame 115
CA1 carbonic anhydrase I
CCL5 chemokine (C-C motif) ligand 5
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CD14 CD14 molecule
CD36 CD36 molecule (thrombospondin receptor)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DUSP6 dual specificity phosphatase 6
GRWD1 glutamate-rich WD repeat containing 1
IER3 immediate early response 3
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT6A keratin 6A, type II
LAMA3 laminin, alpha 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LPL lipoprotein lipase
LTB lymphotoxin beta (TNF superfamily, member 3)
MATN2 matrilin 2
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PRSS21 protease, serine, 21 (testisin)
RGS2 regulator of G-protein signaling 2
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SELENBP1 selenium binding protein 1
SFN stratifin
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SST somatostatin
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TSC22D1 TSC22 domain family, member 1
TSPAN13 tetraspanin 13
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
AGR2 anterior gradient 2
ARMCX1 armadillo repeat containing, X-linked 1
BHLHE41 basic helix-loop-helix family, member e41
CBR3 carbonyl reductase 3
CCNF cyclin F
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CNOT4 CCR4-NOT transcription complex, subunit 4
COL14A1 collagen, type XIV, alpha 1
CPE carboxypeptidase E
DHRS2 dehydrogenase/reductase (SDR family) member 2
DMTF1 cyclin D binding myb-like transcription factor 1
DUSP4 dual specificity phosphatase 4
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FST follistatin
GSPT2 G1 to S phase transition 2
GSTZ1 glutathione S-transferase zeta 1
HOXA10 homeobox A10
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
JAG1 jagged 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KRCC1 lysine-rich coiled-coil 1
KRT19 keratin 19, type I
MGLL monoglyceride lipase
MMP3 matrix metallopeptidase 3
NRCAM neuronal cell adhesion molecule
NT5E 5'-nucleotidase, ecto (CD73)
NUP62 nucleoporin 62kDa
PLAC8 placenta-specific 8
RPS11 ribosomal protein S11
SATB1 SATB homeobox 1
SFRP4 secreted frizzled-related protein 4
SMAD3 SMAD family member 3
SPP1 secreted phosphoprotein 1
SRSF6 serine/arginine-rich splicing factor 6
TCF4 transcription factor 4
TSPYL5 TSPY-like 5