BRD-A60245366_AS-601245_MCF7_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

116 genes differentially expressed following the BRD-A60245366_AS-601245_MCF7_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ACPP acid phosphatase, prostate
AKAP7 A kinase (PRKA) anchor protein 7
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
APOD apolipoprotein D
AQP4 aquaporin 4
CA12 carbonic anhydrase XII
CD99 CD99 molecule
CHI3L2 chitinase 3-like 2
CHPT1 choline phosphotransferase 1
CKAP4 cytoskeleton-associated protein 4
CTSH cathepsin H
CXCL8 chemokine (C-X-C motif) ligand 8
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DSP desmoplakin
E2F2 E2F transcription factor 2
ECI2 enoyl-CoA delta isomerase 2
EGR1 early growth response 1
EGR3 early growth response 3
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EMP1 epithelial membrane protein 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ENDOD1 endonuclease domain containing 1
FABP7 fatty acid binding protein 7, brain
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FOXG1 forkhead box G1
GDF15 growth differentiation factor 15
GYPC glycophorin C (Gerbich blood group)
HIST1H1C histone cluster 1, H1c
HMGA2 high mobility group AT-hook 2
HSDL2 hydroxysteroid dehydrogenase like 2
IGFBP6 insulin-like growth factor binding protein 6
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
KDM5D lysine (K)-specific demethylase 5D
MBP myelin basic protein
MED24 mediator complex subunit 24
NES nestin
NKX3-1 NK3 homeobox 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NT5DC2 5'-nucleotidase domain containing 2
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
PECR peroxisomal trans-2-enoyl-CoA reductase
PLTP phospholipid transfer protein
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPAP2B phosphatidic acid phosphatase type 2B
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RCAN1 regulator of calcineurin 1
RGS2 regulator of G-protein signaling 2
RPS4Y1 ribosomal protein S4, Y-linked 1
SEPP1 selenoprotein P, plasma, 1
SEPT6 septin 6
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SORD sorbitol dehydrogenase
TMEM100 transmembrane protein 100
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSKU tsukushi, small leucine rich proteoglycan
TUBB tubulin, beta class I
TWF1 twinfilin actin binding protein 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAT2 acetyl-CoA acetyltransferase 2
ADD3 adducin 3 (gamma)
ADIRF adipogenesis regulatory factor
ALCAM activated leukocyte cell adhesion molecule
ASPN asporin
BRCA1 breast cancer 1, early onset
CAV1 caveolin 1, caveolae protein, 22kDa
CHN1 chimerin 1
CLC Charcot-Leyden crystal galectin
CLU clusterin
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
COL8A2 collagen, type VIII, alpha 2
CPE carboxypeptidase E
CREB1 cAMP responsive element binding protein 1
CTBP2 C-terminal binding protein 2
DKK3 dickkopf WNT signaling pathway inhibitor 3
ECM1 extracellular matrix protein 1
FOS FBJ murine osteosarcoma viral oncogene homolog
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GLIPR1 GLI pathogenesis-related 1
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HIST1H4C histone cluster 1, H4c
HSPH1 heat shock 105kDa/110kDa protein 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
ICAM2 intercellular adhesion molecule 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
KRT7 keratin 7, type II
LRRC15 leucine rich repeat containing 15
MME membrane metallo-endopeptidase
MMP3 matrix metallopeptidase 3
MT1F metallothionein 1F
MT1M metallothionein 1M
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MZT2B mitotic spindle organizing protein 2B
NMRK1 nicotinamide riboside kinase 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
POSTN periostin, osteoblast specific factor
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PROM1 prominin 1
PTPRK protein tyrosine phosphatase, receptor type, K
RPA3 replication protein A3, 14kDa
SEPHS1 selenophosphate synthetase 1
SLC38A1 solute carrier family 38, member 1
SLC38A2 solute carrier family 38, member 2
SPINK1 serine peptidase inhibitor, Kazal type 1
SULF1 sulfatase 1
TES testin LIM domain protein
TSPYL5 TSPY-like 5
TST thiosulfate sulfurtransferase (rhodanese)
VCAN versican
XIST X inactive specific transcript (non-protein coding)
ZNF721 zinc finger protein 721