BRD-A60245366_AS-601245_A549_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

80 genes differentially expressed following the BRD-A60245366_AS-601245_A549_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AREG amphiregulin
BHMT2 betaine--homocysteine S-methyltransferase 2
CA12 carbonic anhydrase XII
CD36 CD36 molecule (thrombospondin receptor)
CLDN8 claudin 8
CLEC2B C-type lectin domain family 2, member B
COLEC12 collectin sub-family member 12
CYB5A cytochrome b5 type A (microsomal)
DSP desmoplakin
EMX2 empty spiracles homeobox 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FKBP11 FK506 binding protein 11, 19 kDa
GLUL glutamate-ammonia ligase
GPER1 G protein-coupled estrogen receptor 1
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
HLA-C major histocompatibility complex, class I, C
HOPX HOP homeobox
IFITM1 interferon induced transmembrane protein 1
IFITM3 interferon induced transmembrane protein 3
KRT6A keratin 6A, type II
LYN LYN proto-oncogene, Src family tyrosine kinase
MBP myelin basic protein
MME membrane metallo-endopeptidase
MREG melanoregulin
MSX1 msh homeobox 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PI3 peptidase inhibitor 3, skin-derived
PRF1 perforin 1 (pore forming protein)
PRR5 proline rich 5 (renal)
RGCC regulator of cell cycle
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNASE4 ribonuclease, RNase A family, 4
SEPP1 selenoprotein P, plasma, 1
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SPRR1B small proline-rich protein 1B
STXBP1 syntaxin binding protein 1
TBX2 T-box 2
TPSAB1 tryptase alpha/beta 1
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTN1 actinin, alpha 1
ADGRG2 adhesion G protein-coupled receptor G2
ANXA3 annexin A3
ARHGAP29 Rho GTPase activating protein 29
CAV2 caveolin 2
CCP110 centriolar coiled coil protein 110kDa
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CLINT1 clathrin interactor 1
CRISP3 cysteine-rich secretory protein 3
CSRP1 cysteine and glycine-rich protein 1
DES desmin
DHRS2 dehydrogenase/reductase (SDR family) member 2
DUSP3 dual specificity phosphatase 3
FHL1 four and a half LIM domains 1
FN1 fibronectin 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL6ST interleukin 6 signal transducer
KRT18 keratin 18, type I
LYZ lysozyme
NFIB nuclear factor I/B
NNMT nicotinamide N-methyltransferase
PLN phospholamban
PROM1 prominin 1
PTPRO protein tyrosine phosphatase, receptor type, O
PXDN peroxidasin
RBKS ribokinase
RPS11 ribosomal protein S11
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC38A2 solute carrier family 38, member 2
TFPI2 tissue factor pathway inhibitor 2
TOR1A torsin family 1, member A (torsin A)
TRIM14 tripartite motif containing 14
TSPYL5 TSPY-like 5
TXNDC9 thioredoxin domain containing 9