BRD-A59145032_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

66 genes differentially expressed following the BRD-A59145032_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD4 abhydrolase domain containing 4
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
CTH cystathionine gamma-lyase
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FCMR Fc fragment of IgM receptor
FOSL1 FOS-like antigen 1
FOXJ3 forkhead box J3
G6PD glucose-6-phosphate dehydrogenase
GCLM glutamate-cysteine ligase, modifier subunit
HAPLN1 hyaluronan and proteoglycan link protein 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFRD1 interferon-related developmental regulator 1
KLF4 Kruppel-like factor 4 (gut)
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NEFH neurofilament, heavy polypeptide
NFIL3 nuclear factor, interleukin 3 regulated
NKX3-1 NK3 homeobox 1
NR0B1 nuclear receptor subfamily 0, group B, member 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHLDA1 pleckstrin homology-like domain, family A, member 1
POPDC3 popeye domain containing 3
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTN pleiotrophin
RAD23B RAD23 homolog B (S. cerevisiae)
S100A10 S100 calcium binding protein A10
SELL selectin L
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SERTAD2 SERTA domain containing 2
SFN stratifin
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
C7 complement component 7
CCNE2 cyclin E2
CNN1 calponin 1, basic, smooth muscle
COL4A5 collagen, type IV, alpha 5
CPE carboxypeptidase E
DEPTOR DEP domain containing MTOR-interacting protein
DPYSL3 dihydropyrimidinase-like 3
ESR1 estrogen receptor 1
FABP4 fatty acid binding protein 4, adipocyte
FGFR2 fibroblast growth factor receptor 2
FILIP1L filamin A interacting protein 1-like
FOXF1 forkhead box F1
HES1 hes family bHLH transcription factor 1
IGHM immunoglobulin heavy constant mu
LMO2 LIM domain only 2 (rhombotin-like 1)
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC17 leucine rich repeat containing 17
MACF1 microtubule-actin crosslinking factor 1
MEIS2 Meis homeobox 2
NRIP1 nuclear receptor interacting protein 1
POU2AF1 POU class 2 associating factor 1
SFRP1 secreted frizzled-related protein 1
XBP1 X-box binding protein 1