BRD-A58564983_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

33 genes differentially expressed following the BRD-A58564983_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
BAZ2B bromodomain adjacent to zinc finger domain, 2B
CLIC4 chloride intracellular channel 4
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
EDNRB endothelin receptor type B
GARS glycyl-tRNA synthetase
GDF15 growth differentiation factor 15
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IL1R1 interleukin 1 receptor, type I
MBNL2 muscleblind-like splicing regulator 2
NCK1 NCK adaptor protein 1
NFIL3 nuclear factor, interleukin 3 regulated
PHGDH phosphoglycerate dehydrogenase
RSRC2 arginine/serine-rich coiled-coil 2
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
STC2 stanniocalcin 2
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)

decreased expression

Symbol Name
CALR calreticulin
CD9 CD9 molecule
CLIC3 chloride intracellular channel 3
CSRP2 cysteine and glycine-rich protein 2
EMP1 epithelial membrane protein 1
GJA1 gap junction protein, alpha 1, 43kDa
HOPX HOP homeobox
KANK1 KN motif and ankyrin repeat domains 1
KRT5 keratin 5, type II
LMO3 LIM domain only 3 (rhombotin-like 2)
POSTN periostin, osteoblast specific factor
PRDX4 peroxiredoxin 4
S100A8 S100 calcium binding protein A8
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1