BRD-A56592690_PX12_A375_6.0_h_30.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

30 genes differentially expressed following the BRD-A56592690_PX12_A375_6.0_h_30.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANPEP alanyl (membrane) aminopeptidase
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
CD52 CD52 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPYSL3 dihydropyrimidinase-like 3
FABP1 fatty acid binding protein 1, liver
FAM69A family with sequence similarity 69, member A
GAS6 growth arrest-specific 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
MEIS2 Meis homeobox 2
NUPR1 nuclear protein, transcriptional regulator, 1
P3H2 prolyl 3-hydroxylase 2
SHB Src homology 2 domain containing adaptor protein B
TNNT1 troponin T type 1 (skeletal, slow)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C2 aldo-keto reductase family 1, member C2
COL9A3 collagen, type IX, alpha 3
FABP7 fatty acid binding protein 7, brain
FOXC1 forkhead box C1
FOXO1 forkhead box O1
GAS7 growth arrest-specific 7
GCLC glutamate-cysteine ligase, catalytic subunit
NET1 neuroepithelial cell transforming 1
S100B S100 calcium binding protein B
SEPP1 selenoprotein P, plasma, 1
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TMEM47 transmembrane protein 47
UPK1B uroplakin 1B