BRD-A56245458_reichstein/C,Aeos substance/C-*s_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

105 genes differentially expressed following the BRD-A56245458_reichstein/C,Aeos substance/C-*s_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AP2M1 adaptor-related protein complex 2, mu 1 subunit
ARL4C ADP-ribosylation factor-like 4C
ARMCX1 armadillo repeat containing, X-linked 1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
CA2 carbonic anhydrase II
CD163 CD163 molecule
CD34 CD34 molecule
CD52 CD52 molecule
CD93 CD93 molecule
CLEC11A C-type lectin domain family 11, member A
CLGN calmegin
EXT1 exostosin glycosyltransferase 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FHL1 four and a half LIM domains 1
FXR1 fragile X mental retardation, autosomal homolog 1
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KLHL24 kelch-like family member 24
MAP7 microtubule-associated protein 7
MATN2 matrilin 2
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NPTX2 neuronal pentraxin II
NTS neurotensin
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDCD10 programmed cell death 10
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLAU plasminogen activator, urokinase
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PNMA2 paraneoplastic Ma antigen 2
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
PRKCI protein kinase C, iota
PRUNE2 prune homolog 2 (Drosophila)
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PXDN peroxidasin
RGCC regulator of cell cycle
SATB1 SATB homeobox 1
SCG5 secretogranin V
SCN3A sodium channel, voltage gated, type III alpha subunit
SLC38A1 solute carrier family 38, member 1
ST18 suppression of tumorigenicity 18, zinc finger
TMSB15A thymosin beta 15a
VCAN versican
VEGFA vascular endothelial growth factor A
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BCLAF1 BCL2-associated transcription factor 1
BST2 bone marrow stromal cell antigen 2
C2CD2 C2 calcium-dependent domain containing 2
CASP2 caspase 2, apoptosis-related cysteine peptidase
CHPT1 choline phosphotransferase 1
COL9A3 collagen, type IX, alpha 3
CTSH cathepsin H
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCPS decapping enzyme, scavenger
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEFB1 defensin, beta 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
EGR3 early growth response 3
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM198B family with sequence similarity 198, member B
FGF13 fibroblast growth factor 13
FLRT2 fibronectin leucine rich transmembrane protein 2
FOXC1 forkhead box C1
FZD7 frizzled class receptor 7
GNAS GNAS complex locus
GPC3 glypican 3
GSN gelsolin
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFI44L interferon-induced protein 44-like
IFITM3 interferon induced transmembrane protein 3
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
KDM5D lysine (K)-specific demethylase 5D
LAMP1 lysosomal-associated membrane protein 1
LTF lactotransferrin
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
METTL7A methyltransferase like 7A
MGP matrix Gla protein
MX2 MX dynamin-like GTPase 2
NAMPT nicotinamide phosphoribosyltransferase
NBPF10 neuroblastoma breakpoint family, member 10
NR2F2 nuclear receptor subfamily 2, group F, member 2
PEBP1 phosphatidylethanolamine binding protein 1
RPS11 ribosomal protein S11
SET SET nuclear proto-oncogene
SLC43A3 solute carrier family 43, member 3
SLPI secretory leukocyte peptidase inhibitor
SORD sorbitol dehydrogenase
SPATS2L spermatogenesis associated, serine-rich 2-like
SRPX sushi-repeat containing protein, X-linked
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TLR4 toll-like receptor 4
ZNF586 zinc finger protein 586