BRD-A55594068_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

132 genes differentially expressed following the BRD-A55594068_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALCAM activated leukocyte cell adhesion molecule
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA3 annexin A3
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ARMCX3 armadillo repeat containing, X-linked 3
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
BASP1 brain abundant, membrane attached signal protein 1
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD58 CD58 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLIC5 chloride intracellular channel 5
CSTA cystatin A (stefin A)
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL14 chemokine (C-X-C motif) ligand 14
DDIT4 DNA-damage-inducible transcript 4
DHRS9 dehydrogenase/reductase (SDR family) member 9
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DSP desmoplakin
DUSP1 dual specificity phosphatase 1
DUSP3 dual specificity phosphatase 3
DUSP5 dual specificity phosphatase 5
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EMP1 epithelial membrane protein 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EVI2A ecotropic viral integration site 2A
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM134B family with sequence similarity 134, member B
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
GFOD1 glucose-fructose oxidoreductase domain containing 1
GOLT1B golgi transport 1B
GPRC5A G protein-coupled receptor, class C, group 5, member A
HBEGF heparin-binding EGF-like growth factor
HDAC9 histone deacetylase 9
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
ILK integrin-linked kinase
INSIG1 insulin induced gene 1
ISG20 interferon stimulated exonuclease gene 20kDa
JUN jun proto-oncogene
KCNK1 potassium channel, two pore domain subfamily K, member 1
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
KRT14 keratin 14, type I
KRT16 keratin 16, type I
KRT17 keratin 17, type I
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KRT7 keratin 7, type II
LDLR low density lipoprotein receptor
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1B microtubule-associated protein 1B
MAP7 microtubule-associated protein 7
MCL1 myeloid cell leukemia 1
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MSMO1 methylsterol monooxygenase 1
MT1X metallothionein 1X
MT2A metallothionein 2A
NPC1 Niemann-Pick disease, type C1
ODC1 ornithine decarboxylase 1
OPN3 opsin 3
PALLD palladin, cytoskeletal associated protein
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAU plasminogen activator, urokinase
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PLXNC1 plexin C1
PPARD peroxisome proliferator-activated receptor delta
PRSS23 protease, serine, 23
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
S100A14 S100 calcium binding protein A14
SERP1 stress-associated endoplasmic reticulum protein 1
SFN stratifin
SMAD3 SMAD family member 3
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SPRR2B small proline-rich protein 2B
STX1A syntaxin 1A (brain)
TACSTD2 tumor-associated calcium signal transducer 2
THBS1 thrombospondin 1
TIMP3 TIMP metallopeptidase inhibitor 3
TPM1 tropomyosin 1 (alpha)
UFM1 ubiquitin-fold modifier 1
XBP1 X-box binding protein 1

decreased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALOX5 arachidonate 5-lipoxygenase
CCND2 cyclin D2
CCNF cyclin F
CYBA cytochrome b-245, alpha polypeptide
DHRS2 dehydrogenase/reductase (SDR family) member 2
FZD7 frizzled class receptor 7
GATA2 GATA binding protein 2
GBP2 guanylate binding protein 2, interferon-inducible
HMOX1 heme oxygenase 1
HOXA5 homeobox A5
HP haptoglobin
IL17RB interleukin 17 receptor B
ITM2A integral membrane protein 2A
ITPKB inositol-trisphosphate 3-kinase B
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MGP matrix Gla protein
OBSL1 obscurin-like 1
PDZK1 PDZ domain containing 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
QPRT quinolinate phosphoribosyltransferase
RAP1GAP RAP1 GTPase activating protein
RBP1 retinol binding protein 1, cellular
REG3A regenerating islet-derived 3 alpha
RNASET2 ribonuclease T2
SALL2 spalt-like transcription factor 2
SFRP1 secreted frizzled-related protein 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TNS1 tensin 1
TRIB2 tribbles pseudokinase 2
WNT5A wingless-type MMTV integration site family, member 5A