BRD-A54927599_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

53 genes differentially expressed following the BRD-A54927599_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMOTL2 angiomotin like 2
ANXA1 annexin A1
ATF3 activating transcription factor 3
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHIC2 cysteine-rich hydrophobic domain 2
CSRP2 cysteine and glycine-rich protein 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FBN2 fibrillin 2
G0S2 G0/G1 switch 2
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GPM6B glycoprotein M6B
HMOX1 heme oxygenase 1
KRT23 keratin 23, type I
KRT5 keratin 5, type II
LPL lipoprotein lipase
MATN2 matrilin 2
MT1X metallothionein 1X
NAV2 neuron navigator 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NQO1 NAD(P)H dehydrogenase, quinone 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLBD1 phospholipase B domain containing 1
RND3 Rho family GTPase 3
STC2 stanniocalcin 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
UPP1 uridine phosphorylase 1
VTCN1 V-set domain containing T cell activation inhibitor 1
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
AMACR alpha-methylacyl-CoA racemase
BASP1 brain abundant, membrane attached signal protein 1
BIK BCL2-interacting killer (apoptosis-inducing)
C3 complement component 3
CLEC2B C-type lectin domain family 2, member B
CLIC4 chloride intracellular channel 4
COL10A1 collagen, type X, alpha 1
DCN decorin
GPNMB glycoprotein (transmembrane) nmb
HES1 hes family bHLH transcription factor 1
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
IGFBP6 insulin-like growth factor binding protein 6
KIAA0101 KIAA0101
LXN latexin
MAP7 microtubule-associated protein 7
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PODXL podocalyxin-like
SEPP1 selenoprotein P, plasma, 1
SLC44A4 solute carrier family 44, member 4
SPON1 spondin 1, extracellular matrix protein
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TIMP3 TIMP metallopeptidase inhibitor 3
TOP2A topoisomerase (DNA) II alpha 170kDa
ZDHHC11 zinc finger, DHHC-type containing 11