BRD-A54927599_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

110 genes differentially expressed following the BRD-A54927599_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALCAM activated leukocyte cell adhesion molecule
ANXA3 annexin A3
BASP1 brain abundant, membrane attached signal protein 1
BMP2 bone morphogenetic protein 2
CAB39 calcium binding protein 39
CALML3 calmodulin-like 3
CAPG capping protein (actin filament), gelsolin-like
CD24 CD24 molecule
CD58 CD58 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLU clusterin
CRCT1 cysteine-rich C-terminal 1
CST1 cystatin SN
DSC2 desmocollin 2
DSG3 desmoglein 3
DSP desmoplakin
DUSP14 dual specificity phosphatase 14
ECM1 extracellular matrix protein 1
EMP1 epithelial membrane protein 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FBN2 fibrillin 2
FGFBP1 fibroblast growth factor binding protein 1
FHL2 four and a half LIM domains 2
FILIP1L filamin A interacting protein 1-like
FOSL1 FOS-like antigen 1
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
HBEGF heparin-binding EGF-like growth factor
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOPX HOP homeobox
IGFBP7 insulin-like growth factor binding protein 7
JUN jun proto-oncogene
KLF6 Kruppel-like factor 6
KLK10 kallikrein-related peptidase 10
KRT16 keratin 16, type I
KRT17 keratin 17, type I
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
LDLR low density lipoprotein receptor
LY6D lymphocyte antigen 6 complex, locus D
LYPD3 LY6/PLAUR domain containing 3
MAST2 microtubule associated serine/threonine kinase 2
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MXRA7 matrix-remodelling associated 7
NELL2 NEL-like 2 (chicken)
PALLD palladin, cytoskeletal associated protein
PHLDA1 pleckstrin homology-like domain, family A, member 1
PI3 peptidase inhibitor 3, skin-derived
PKP1 plakophilin 1
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PMEPA1 prostate transmembrane protein, androgen induced 1
PPARD peroxisome proliferator-activated receptor delta
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PRSS23 protease, serine, 23
PRSS3 protease, serine, 3
RBP1 retinol binding protein 1, cellular
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHOD ras homolog family member D
RNF167 ring finger protein 167
S100A14 S100 calcium binding protein A14
S100A2 S100 calcium binding protein A2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SFN stratifin
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SPRR2B small proline-rich protein 2B
SPRR3 small proline-rich protein 3
TACSTD2 tumor-associated calcium signal transducer 2
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TPM1 tropomyosin 1 (alpha)
TSC22D2 TSC22 domain family, member 2
TUBB2A tubulin, beta 2A class IIa
UGCG UDP-glucose ceramide glucosyltransferase

decreased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ASRGL1 asparaginase like 1
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
BHLHE41 basic helix-loop-helix family, member e41
ETV5 ets variant 5
FBLN1 fibulin 1
GAS1 growth arrest-specific 1
HNMT histamine N-methyltransferase
HOXA10 homeobox A10
LUM lumican
MCOLN1 mucolipin 1
MYRF myelin regulatory factor
NDNF neuron-derived neurotrophic factor
NEFH neurofilament, heavy polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PEG10 paternally expressed 10
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PPAP2B phosphatidic acid phosphatase type 2B
PTGIS prostaglandin I2 (prostacyclin) synthase
RAP1GAP RAP1 GTPase activating protein
RNASET2 ribonuclease T2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRGN serglycin
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TNS3 tensin 3
TOX3 TOX high mobility group box family member 3
TRIM2 tripartite motif containing 2