BRD-A54632525_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-A54632525_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDOC aldolase C, fructose-bisphosphate
ASNS asparagine synthetase (glutamine-hydrolyzing)
AXL AXL receptor tyrosine kinase
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CFB complement factor B
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CXCL8 chemokine (C-X-C motif) ligand 8
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DSP desmoplakin
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
FGFR3 fibroblast growth factor receptor 3
G0S2 G0/G1 switch 2
GLUL glutamate-ammonia ligase
GPM6B glycoprotein M6B
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
IFITM1 interferon induced transmembrane protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
JCHAIN joining chain of multimeric IgA and IgM
KDM4B lysine (K)-specific demethylase 4B
KDM5D lysine (K)-specific demethylase 5D
LRRC15 leucine rich repeat containing 15
LTF lactotransferrin
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
ORM1 orosomucoid 1
PDGFA platelet-derived growth factor alpha polypeptide
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SLPI secretory leukocyte peptidase inhibitor
TNIP1 TNFAIP3 interacting protein 1
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
CDKN2A cyclin-dependent kinase inhibitor 2A
COL3A1 collagen, type III, alpha 1
DCLK1 doublecortin-like kinase 1
DMD dystrophin
FBXL12 F-box and leucine-rich repeat protein 12
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HSPA1A heat shock 70kDa protein 1A
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
KIF20A kinesin family member 20A
LAPTM4B lysosomal protein transmembrane 4 beta
LRP2 low density lipoprotein receptor-related protein 2
MMP7 matrix metallopeptidase 7
MPPED2 metallophosphoesterase domain containing 2
PRUNE2 prune homolog 2 (Drosophila)
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
WT1 Wilms tumor 1
XIST X inactive specific transcript (non-protein coding)