BRD-A51410489_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

33 genes differentially expressed following the BRD-A51410489_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
ACTN1 actinin, alpha 1
ALOX5 arachidonate 5-lipoxygenase
CCL19 chemokine (C-C motif) ligand 19
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
FGF13 fibroblast growth factor 13
GZMK granzyme K (granzyme 3; tryptase II)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IL6ST interleukin 6 signal transducer
LCN2 lipocalin 2
QPCT glutaminyl-peptide cyclotransferase
S100A8 S100 calcium binding protein A8
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TACSTD2 tumor-associated calcium signal transducer 2

decreased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ANGPTL2 angiopoietin-like 2
CPT1A carnitine palmitoyltransferase 1A (liver)
FABP1 fatty acid binding protein 1, liver
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGFBP5 insulin-like growth factor binding protein 5
IGHD immunoglobulin heavy constant delta
IGKV1-5 immunoglobulin kappa variable 1-5
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PTN pleiotrophin
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SCG2 secretogranin II
SEPP1 selenoprotein P, plasma, 1
SFRP4 secreted frizzled-related protein 4
SPINK1 serine peptidase inhibitor, Kazal type 1
THBS1 thrombospondin 1