BRD-A50737080_CGK-733_HCC515_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-A50737080_CGK-733_HCC515_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
AQP3 aquaporin 3 (Gill blood group)
CADM1 cell adhesion molecule 1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CPB1 carboxypeptidase B1 (tissue)
CXADR coxsackie virus and adenovirus receptor
CXCL14 chemokine (C-X-C motif) ligand 14
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
ELOVL5 ELOVL fatty acid elongase 5
ENO2 enolase 2 (gamma, neuronal)
FTO fat mass and obesity associated
GRIA2 glutamate receptor, ionotropic, AMPA 2
HBB hemoglobin, beta
HSPA2 heat shock 70kDa protein 2
IL1R2 interleukin 1 receptor, type II
LEF1 lymphoid enhancer-binding factor 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP7 microtubule-associated protein 7
MFAP3L microfibrillar-associated protein 3-like
MMP9 matrix metallopeptidase 9
MRPS30 mitochondrial ribosomal protein S30
PLAT plasminogen activator, tissue
PRPS2 phosphoribosyl pyrophosphate synthetase 2
RTN1 reticulon 1
SCGB2A2 secretoglobin, family 2A, member 2
SFN stratifin
SLC39A8 solute carrier family 39 (zinc transporter), member 8
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
TIAM1 T-cell lymphoma invasion and metastasis 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANXA3 annexin A3
CYR61 cysteine-rich, angiogenic inducer, 61
GSTM3 glutathione S-transferase mu 3 (brain)
HILPDA hypoxia inducible lipid droplet-associated
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HN1 hematological and neurological expressed 1
HOPX HOP homeobox
IGFBP4 insulin-like growth factor binding protein 4
IGHM immunoglobulin heavy constant mu
LOXL2 lysyl oxidase-like 2
MN1 meningioma (disrupted in balanced translocation) 1
MYRF myelin regulatory factor
PDZK1IP1 PDZK1 interacting protein 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
RPS26 ribosomal protein S26
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
TACSTD2 tumor-associated calcium signal transducer 2
TPM1 tropomyosin 1 (alpha)
ZNF185 zinc finger protein 185 (LIM domain)