BRD-A50737080_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

29 genes differentially expressed following the BRD-A50737080_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CA2 carbonic anhydrase II
CBS cystathionine-beta-synthase
CFB complement factor B
CXCL6 chemokine (C-X-C motif) ligand 6
FAM129A family with sequence similarity 129, member A
IER5 immediate early response 5
IFRD1 interferon-related developmental regulator 1
KRT23 keratin 23, type I
METTL7A methyltransferase like 7A
MMP3 matrix metallopeptidase 3
MOCOS molybdenum cofactor sulfurase
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYC v-myc avian myelocytomatosis viral oncogene homolog
PADI2 peptidyl arginine deiminase, type II
PDGFC platelet derived growth factor C
PHLDA1 pleckstrin homology-like domain, family A, member 1
PXDN peroxidasin
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
STC2 stanniocalcin 2
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
VCAM1 vascular cell adhesion molecule 1

decreased expression

Symbol Name
CDC25A cell division cycle 25A
FASN fatty acid synthase
LMO3 LIM domain only 3 (rhombotin-like 2)
MAOA monoamine oxidase A
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
TSPAN7 tetraspanin 7