BRD-A50675702_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

28 genes differentially expressed following the BRD-A50675702_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMIGO2 adhesion molecule with Ig-like domain 2
CA2 carbonic anhydrase II
DAAM1 dishevelled associated activator of morphogenesis 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
FAM129A family with sequence similarity 129, member A
GPRC5B G protein-coupled receptor, class C, group 5, member B
GRB7 growth factor receptor-bound protein 7
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MMP3 matrix metallopeptidase 3
RBP1 retinol binding protein 1, cellular
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TPD52L1 tumor protein D52-like 1
VCL vinculin
WT1 Wilms tumor 1

decreased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
CDC42 cell division cycle 42
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
DERA deoxyribose-phosphate aldolase (putative)
IGHD immunoglobulin heavy constant delta
LOX lysyl oxidase
MAOA monoamine oxidase A
MSMB microseminoprotein, beta-
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
TMEM243 transmembrane protein 243, mitochondrial