BRD-A50675702_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

61 genes differentially expressed following the BRD-A50675702_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLIC4 chloride intracellular channel 4
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
FHL2 four and a half LIM domains 2
GAA glucosidase, alpha; acid
GARS glycyl-tRNA synthetase
GDF15 growth differentiation factor 15
GPM6B glycoprotein M6B
IGFBP4 insulin-like growth factor binding protein 4
KLK10 kallikrein-related peptidase 10
LCN2 lipocalin 2
MOCOS molybdenum cofactor sulfurase
NEBL nebulette
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
PRSS23 protease, serine, 23
PSAT1 phosphoserine aminotransferase 1
QPCT glutaminyl-peptide cyclotransferase
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMAD3 SMAD family member 3
SPRED2 sprouty-related, EVH1 domain containing 2
TNS3 tensin 3
TSC22D3 TSC22 domain family, member 3
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
VAT1 vesicle amine transport 1
VEGFA vascular endothelial growth factor A
WARS tryptophanyl-tRNA synthetase

decreased expression

Symbol Name
CDK6 cyclin-dependent kinase 6
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
EFNB2 ephrin-B2
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EVL Enah/Vasp-like
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FOLR1 folate receptor 1 (adult)
GHR growth hormone receptor
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2BE histone cluster 1, H2be
HIST1H2BF histone cluster 1, H2bf
HIST1H2BH histone cluster 1, H2bh
HIST1H2BK histone cluster 1, H2bk
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
LTF lactotransferrin
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
SC5D sterol-C5-desaturase
TUBA4A tubulin, alpha 4a