BRD-A49848186_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

111 genes differentially expressed following the BRD-A49848186_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA1 annexin A1
APOC1 apolipoprotein C-I
ATF3 activating transcription factor 3
BAG3 BCL2-associated athanogene 3
BAMBI BMP and activin membrane-bound inhibitor
BID BH3 interacting domain death agonist
BMP4 bone morphogenetic protein 4
BPHL biphenyl hydrolase-like (serine hydrolase)
CD200 CD200 molecule
CD24 CD24 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CRABP1 cellular retinoic acid binding protein 1
CRELD2 cysteine-rich with EGF-like domains 2
CRIP2 cysteine-rich protein 2
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
DDIT3 DNA-damage-inducible transcript 3
DMTF1 cyclin D binding myb-like transcription factor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP1 dual specificity phosphatase 1
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45B growth arrest and DNA-damage-inducible, beta
GATA2 GATA binding protein 2
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HES1 hes family bHLH transcription factor 1
HIST1H2AE histone cluster 1, H2ae
HIST1H2BG histone cluster 1, H2bg
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IER5 immediate early response 5
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
JUNB jun B proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
KRT5 keratin 5, type II
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
PELI1 pellino E3 ubiquitin protein ligase 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTGDS prostaglandin D2 synthase 21kDa (brain)
RGS2 regulator of G-protein signaling 2
RPL39L ribosomal protein L39-like
S100A10 S100 calcium binding protein A10
S100A8 S100 calcium binding protein A8
SCGB2A2 secretoglobin, family 2A, member 2
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SRSF7 serine/arginine-rich splicing factor 7
TCTN1 tectonic family member 1
TRIB1 tribbles pseudokinase 1
TXNL4B thioredoxin-like 4B
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
AKAP11 A kinase (PRKA) anchor protein 11
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ASPN asporin
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BACE2 beta-site APP-cleaving enzyme 2
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BST2 bone marrow stromal cell antigen 2
BTBD3 BTB (POZ) domain containing 3
COL4A5 collagen, type IV, alpha 5
COL5A1 collagen, type V, alpha 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DHRS1 dehydrogenase/reductase (SDR family) member 1
DLG5 discs, large homolog 5 (Drosophila)
DMD dystrophin
EBP emopamil binding protein (sterol isomerase)
EDNRA endothelin receptor type A
FAM57A family with sequence similarity 57, member A
GLIPR1 GLI pathogenesis-related 1
GRWD1 glutamate-rich WD repeat containing 1
HOXA5 homeobox A5
ICAM1 intercellular adhesion molecule 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
LPCAT1 lysophosphatidylcholine acyltransferase 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MGP matrix Gla protein
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MSLN mesothelin
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PRDX2 peroxiredoxin 2
PSD3 pleckstrin and Sec7 domain containing 3
RAB31 RAB31, member RAS oncogene family
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RPS11 ribosomal protein S11
SELENBP1 selenium binding protein 1
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLK STE20-like kinase
SUB1 SUB1 homolog (S. cerevisiae)
TNS1 tensin 1
TSPYL4 TSPY-like 4
USP9X ubiquitin specific peptidase 9, X-linked
WDR6 WD repeat domain 6
WRB tryptophan rich basic protein
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
ZBTB18 zinc finger and BTB domain containing 18
ZNF185 zinc finger protein 185 (LIM domain)