BRD-A49765801_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

85 genes differentially expressed following the BRD-A49765801_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADCY9 adenylate cyclase 9
ALB albumin
CCDC86 coiled-coil domain containing 86
COL4A5 collagen, type IV, alpha 5
CPE carboxypeptidase E
CRABP1 cellular retinoic acid binding protein 1
CXADR coxsackie virus and adenovirus receptor
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DLK1 delta-like 1 homolog (Drosophila)
FAM69A family with sequence similarity 69, member A
FBXL12 F-box and leucine-rich repeat protein 12
FCGBP Fc fragment of IgG binding protein
FOLR1 folate receptor 1 (adult)
GNLY granulysin
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP5 insulin-like growth factor binding protein 5
IGL immunoglobulin lambda locus
IL1R1 interleukin 1 receptor, type I
IPO13 importin 13
JADE2 jade family PHD finger 2
JCHAIN joining chain of multimeric IgA and IgM
KRT19 keratin 19, type I
KRT7 keratin 7, type II
LOC100505650 uncharacterized LOC100505650
LPCAT1 lysophosphatidylcholine acyltransferase 1
METTL7A methyltransferase like 7A
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MTSS1 metastasis suppressor 1
MUC16 mucin 16, cell surface associated
OSBPL10 oxysterol binding protein-like 10
PEG10 paternally expressed 10
PLAU plasminogen activator, urokinase
PRSS21 protease, serine, 21 (testisin)
PRUNE2 prune homolog 2 (Drosophila)
RGCC regulator of cell cycle
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SELENBP1 selenium binding protein 1
SFRP1 secreted frizzled-related protein 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SOCS1 suppressor of cytokine signaling 1
SPTSSA serine palmitoyltransferase, small subunit A
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)

decreased expression

Symbol Name
ANXA1 annexin A1
ANXA3 annexin A3
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BACE2 beta-site APP-cleaving enzyme 2
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
DAPK1 death-associated protein kinase 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
ELOVL5 ELOVL fatty acid elongase 5
EPHA3 EPH receptor A3
FHL1 four and a half LIM domains 1
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
HOXC6 homeobox C6
IER3 immediate early response 3
KRT14 keratin 14, type I
LAMB1 laminin, beta 1
LDHB lactate dehydrogenase B
MAGED1 melanoma antigen family D1
MARCKS myristoylated alanine-rich protein kinase C substrate
MET MET proto-oncogene, receptor tyrosine kinase
NEFL neurofilament, light polypeptide
NOTCH3 notch 3
NRN1 neuritin 1
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
PDLIM5 PDZ and LIM domain 5
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
RGS2 regulator of G-protein signaling 2
SLC16A4 solute carrier family 16, member 4
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TCAF1 TRPM8 channel-associated factor 1
TIMP3 TIMP metallopeptidase inhibitor 3
TM4SF4 transmembrane 4 L six family member 4
ZIC1 Zic family member 1