BRD-A49680073_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

84 genes differentially expressed following the BRD-A49680073_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTA1 actin, alpha 1, skeletal muscle
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ATF3 activating transcription factor 3
C5AR1 complement component 5a receptor 1
CASP7 caspase 7, apoptosis-related cysteine peptidase
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CLIC4 chloride intracellular channel 4
CNPY3 canopy FGF signaling regulator 3
CSRP2 cysteine and glycine-rich protein 2
CTGF connective tissue growth factor
CTSL cathepsin L
DDIT3 DNA-damage-inducible transcript 3
EMP1 epithelial membrane protein 1
EZR ezrin
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM129A family with sequence similarity 129, member A
FERMT2 fermitin family member 2
FOSL2 FOS-like antigen 2
GPM6B glycoprotein M6B
HBEGF heparin-binding EGF-like growth factor
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IFI44L interferon-induced protein 44-like
IRF7 interferon regulatory factor 7
ISG20 interferon stimulated exonuclease gene 20kDa
KLF2 Kruppel-like factor 2
KLF4 Kruppel-like factor 4 (gut)
KLF9 Kruppel-like factor 9
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MARS methionyl-tRNA synthetase
MICALL1 MICAL-like 1
MIR22HG MIR22 host gene
MX1 MX dynamin-like GTPase 1
NPC1 Niemann-Pick disease, type C1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDLIM5 PDZ and LIM domain 5
PHLDA1 pleckstrin homology-like domain, family A, member 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPARD peroxisome proliferator-activated receptor delta
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RIOK3 RIO kinase 3
S100A2 S100 calcium binding protein A2
S100P S100 calcium binding protein P
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
THBD thrombomodulin
TICAM1 toll-like receptor adaptor molecule 1
TNIP1 TNFAIP3 interacting protein 1
TPM1 tropomyosin 1 (alpha)
TSC22D3 TSC22 domain family, member 3
TUBB2A tubulin, beta 2A class IIa
TXNIP thioredoxin interacting protein
UGDH UDP-glucose 6-dehydrogenase
UPP1 uridine phosphorylase 1
VWF von Willebrand factor
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
BIRC5 baculoviral IAP repeat containing 5
CCNA2 cyclin A2
CCNF cyclin F
ETV5 ets variant 5
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HOXA10 homeobox A10
IMP3 IMP3, U3 small nucleolar ribonucleoprotein
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
MEIS1 Meis homeobox 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
SFRP4 secreted frizzled-related protein 4
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPON2 spondin 2, extracellular matrix protein
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TFRC transferrin receptor
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TRIB2 tribbles pseudokinase 2
WT1 Wilms tumor 1