BRD-A49225603_TRIMEPRAZINE TARTRATE_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-A49225603_TRIMEPRAZINE TARTRATE_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACLY ATP citrate lyase
ALCAM activated leukocyte cell adhesion molecule
BEX1 brain expressed, X-linked 1
C8ORF4 chromosome 8 open reading frame 4
CCND1 cyclin D1
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CSRP1 cysteine and glycine-rich protein 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
DKK1 dickkopf WNT signaling pathway inhibitor 1
EBP emopamil binding protein (sterol isomerase)
ELOVL6 ELOVL fatty acid elongase 6
FADS1 fatty acid desaturase 1
FDPS farnesyl diphosphate synthase
FOXO3 forkhead box O3
GCH1 GTP cyclohydrolase 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
LDLR low density lipoprotein receptor
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MSMO1 methylsterol monooxygenase 1
NPY neuropeptide Y
NSDHL NAD(P) dependent steroid dehydrogenase-like
PENK proenkephalin
RAMP1 receptor (G protein-coupled) activity modifying protein 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SQLE squalene epoxidase
STXBP1 syntaxin binding protein 1
TNPO1 transportin 1
TSPAN8 tetraspanin 8

decreased expression

Symbol Name
CA1 carbonic anhydrase I
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FAM69A family with sequence similarity 69, member A
HBB hemoglobin, beta
INHBB inhibin, beta B
OLFML2A olfactomedin-like 2A
S100A8 S100 calcium binding protein A8
VTCN1 V-set domain containing T cell activation inhibitor 1