BRD-A48631911_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-A48631911_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOE apolipoprotein E
ARMCX2 armadillo repeat containing, X-linked 2
C3 complement component 3
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CFB complement factor B
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL14 chemokine (C-X-C motif) ligand 14
EMP1 epithelial membrane protein 1
F13A1 coagulation factor XIII, A1 polypeptide
FDFT1 farnesyl-diphosphate farnesyltransferase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IDI1 isopentenyl-diphosphate delta isomerase 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP7 insulin-like growth factor binding protein 7
IL17RB interleukin 17 receptor B
INSIG1 insulin induced gene 1
IPO13 importin 13
KCTD12 potassium channel tetramerization domain containing 12
LDLR low density lipoprotein receptor
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MSMO1 methylsterol monooxygenase 1
PSD3 pleckstrin and Sec7 domain containing 3
SCML1 sex comb on midleg-like 1 (Drosophila)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLPI secretory leukocyte peptidase inhibitor
SRGN serglycin
TRAM2 translocation associated membrane protein 2
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
AEBP1 AE binding protein 1
ASCL1 achaete-scute family bHLH transcription factor 1
BMP2 bone morphogenetic protein 2
CDK6 cyclin-dependent kinase 6
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM46A family with sequence similarity 46, member A
MAT2A methionine adenosyltransferase II, alpha
PDLIM5 PDZ and LIM domain 5
RBP1 retinol binding protein 1, cellular
RHOBTB3 Rho-related BTB domain containing 3