BRD-A48237631_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

44 genes differentially expressed following the BRD-A48237631_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AKR1C3 aldo-keto reductase family 1, member C3
ALOX5 arachidonate 5-lipoxygenase
ANKRD10 ankyrin repeat domain 10
BASP1 brain abundant, membrane attached signal protein 1
CCL13 chemokine (C-C motif) ligand 13
DDB2 damage-specific DNA binding protein 2, 48kDa
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DUSP10 dual specificity phosphatase 10
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FAS Fas cell surface death receptor
FOSL1 FOS-like antigen 1
GDF15 growth differentiation factor 15
KDM5D lysine (K)-specific demethylase 5D
KLF4 Kruppel-like factor 4 (gut)
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LMNA lamin A/C
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RPS4Y1 ribosomal protein S4, Y-linked 1
SEPP1 selenoprotein P, plasma, 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SESN1 sestrin 1
SFN stratifin
SIK1 salt-inducible kinase 1
TGFBI transforming growth factor, beta-induced, 68kDa
TOB1 transducer of ERBB2, 1
TXNIP thioredoxin interacting protein
ZDHHC11 zinc finger, DHHC-type containing 11

decreased expression

Symbol Name
CNPY3 canopy FGF signaling regulator 3
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
LAMA4 laminin, alpha 4
LMNB1 lamin B1
LPL lipoprotein lipase
MATN2 matrilin 2
NFIB nuclear factor I/B
PAM peptidylglycine alpha-amidating monooxygenase
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PXDN peroxidasin
RGS1 regulator of G-protein signaling 1
XIST X inactive specific transcript (non-protein coding)