BRD-A47832959_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-A47832959_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTN1 actinin, alpha 1
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CCL20 chemokine (C-C motif) ligand 20
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CREM cAMP responsive element modulator
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
FAM129A family with sequence similarity 129, member A
GCH1 GTP cyclohydrolase 1
GEM GTP binding protein overexpressed in skeletal muscle
GLRX glutaredoxin (thioltransferase)
GPX3 glutathione peroxidase 3
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOXB7 homeobox B7
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB8 heat shock 22kDa protein 8
KRT23 keratin 23, type I
LCN2 lipocalin 2
LMO4 LIM domain only 4
LTF lactotransferrin
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MKNK1 MAP kinase interacting serine/threonine kinase 1
MMD monocyte to macrophage differentiation-associated
MMP7 matrix metallopeptidase 7
NTS neurotensin
OSBPL8 oxysterol binding protein-like 8
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4D phosphodiesterase 4D, cAMP-specific
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
REG1A regenerating islet-derived 1 alpha
SAT1 spermidine/spermine N1-acetyltransferase 1
SCGB2A1 secretoglobin, family 2A, member 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SNAP23 synaptosomal-associated protein, 23kDa
SOD2 superoxide dismutase 2, mitochondrial
SPP1 secreted phosphoprotein 1
STEAP1 six transmembrane epithelial antigen of the prostate 1
TBX3 T-box 3
TFPI2 tissue factor pathway inhibitor 2
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRIB2 tribbles pseudokinase 2
UGCG UDP-glucose ceramide glucosyltransferase
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VLDLR very low density lipoprotein receptor
WFDC2 WAP four-disulfide core domain 2

decreased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
AGR2 anterior gradient 2
ALCAM activated leukocyte cell adhesion molecule
BEX1 brain expressed, X-linked 1
COL5A1 collagen, type V, alpha 1
CREB3L2 cAMP responsive element binding protein 3-like 2
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
FABP1 fatty acid binding protein 1, liver
GPRC5A G protein-coupled receptor, class C, group 5, member A
HN1 hematological and neurological expressed 1
IGHM immunoglobulin heavy constant mu
IQGAP1 IQ motif containing GTPase activating protein 1
LAMB1 laminin, beta 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFIB nuclear factor I/B
PCM1 pericentriolar material 1
PRMT1 protein arginine methyltransferase 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SFTPB surfactant protein B
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SOBP sine oculis binding protein homolog (Drosophila)
SRPX sushi-repeat containing protein, X-linked
TFF3 trefoil factor 3 (intestinal)
ZNF185 zinc finger protein 185 (LIM domain)