BRD-A47816767_-666_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

96 genes differentially expressed following the BRD-A47816767_-666_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADM adrenomedullin
AK4 adenylate kinase 4
ALDOC aldolase C, fructose-bisphosphate
BHLHE40 basic helix-loop-helix family, member e40
BMP2 bone morphogenetic protein 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CADM1 cell adhesion molecule 1
CD200 CD200 molecule
CD300A CD300a molecule
CFH complement factor H
COL11A1 collagen, type XI, alpha 1
CORO1A coronin, actin binding protein, 1A
CYBA cytochrome b-245, alpha polypeptide
DDIT4 DNA-damage-inducible transcript 4
EGLN3 egl-9 family hypoxia-inducible factor 3
ENO1 enolase 1, (alpha)
ENO2 enolase 2 (gamma, neuronal)
FAM162A family with sequence similarity 162, member A
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
GPI glucose-6-phosphate isomerase
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HILPDA hypoxia inducible lipid droplet-associated
HK2 hexokinase 2
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
INSM1 insulinoma-associated 1
KDM3A lysine (K)-specific demethylase 3A
MXI1 MAX interactor 1, dimerization protein
MYH11 myosin, heavy chain 11, smooth muscle
NARF nuclear prelamin A recognition factor
NDRG1 N-myc downstream regulated 1
NRCAM neuronal cell adhesion molecule
ORC1 origin recognition complex, subunit 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PECAM1 platelet/endothelial cell adhesion molecule 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGK1 phosphoglycerate kinase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PTPRK protein tyrosine phosphatase, receptor type, K
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RGS1 regulator of G-protein signaling 1
RNASET2 ribonuclease T2
RRAGD Ras-related GTP binding D
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCGB2A1 secretoglobin, family 2A, member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX4 SRY (sex determining region Y)-box 4
SQLE squalene epoxidase
STC1 stanniocalcin 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VEGFA vascular endothelial growth factor A
VGLL4 vestigial-like family member 4
ZNF292 zinc finger protein 292

decreased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANPEP alanyl (membrane) aminopeptidase
AQP3 aquaporin 3 (Gill blood group)
BAZ1A bromodomain adjacent to zinc finger domain, 1A
C6ORF48 chromosome 6 open reading frame 48
CCNA2 cyclin A2
CCNF cyclin F
CDC25B cell division cycle 25B
CDKN3 cyclin-dependent kinase inhibitor 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHPT1 choline phosphotransferase 1
CST3 cystatin C
CTPS1 CTP synthase 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FBP1 fructose-1,6-bisphosphatase 1
FPGS folylpolyglutamate synthase
GATA2 GATA binding protein 2
HES1 hes family bHLH transcription factor 1
IGFBP3 insulin-like growth factor binding protein 3
IGFBP6 insulin-like growth factor binding protein 6
IRX5 iroquois homeobox 5
KIF20A kinesin family member 20A
MSL1 male-specific lethal 1 homolog (Drosophila)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NET1 neuroepithelial cell transforming 1
NOP56 NOP56 ribonucleoprotein
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PSD3 pleckstrin and Sec7 domain containing 3
PTX3 pentraxin 3, long
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RRAGA Ras-related GTP binding A
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A8 S100 calcium binding protein A8
SERBP1 SERPINE1 mRNA binding protein 1
TM4SF1 transmembrane 4 L six family member 1
TOP2A topoisomerase (DNA) II alpha 170kDa
UBE2C ubiquitin-conjugating enzyme E2C