BRD-A47816767_-666_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

86 genes differentially expressed following the BRD-A47816767_-666_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADM adrenomedullin
AK4 adenylate kinase 4
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ARL4C ADP-ribosylation factor-like 4C
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BPHL biphenyl hydrolase-like (serine hydrolase)
BTG2 BTG family, member 2
CCNE2 cyclin E2
CD9 CD9 molecule
CDC42 cell division cycle 42
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CKB creatine kinase, brain
CSRP2 cysteine and glycine-rich protein 2
DDIT4 DNA-damage-inducible transcript 4
EGLN3 egl-9 family hypoxia-inducible factor 3
ENO2 enolase 2 (gamma, neuronal)
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
HSPA13 heat shock protein 70kDa family, member 13
HSPA1A heat shock 70kDa protein 1A
IGFBP3 insulin-like growth factor binding protein 3
IL32 interleukin 32
IRF7 interferon regulatory factor 7
KDM3A lysine (K)-specific demethylase 3A
LOX lysyl oxidase
LSP1 lymphocyte-specific protein 1
LTB lymphotoxin beta (TNF superfamily, member 3)
NDRG1 N-myc downstream regulated 1
OXSR1 oxidative stress responsive 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PDGFA platelet-derived growth factor alpha polypeptide
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGK1 phosphoglycerate kinase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PTN pleiotrophin
RECQL RecQ helicase-like
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SNX7 sorting nexin 7
TOB1 transducer of ERBB2, 1
TSPAN13 tetraspanin 13
TXNIP thioredoxin interacting protein
UPP1 uridine phosphorylase 1
VGLL4 vestigial-like family member 4
VTCN1 V-set domain containing T cell activation inhibitor 1
WSB1 WD repeat and SOCS box containing 1

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANPEP alanyl (membrane) aminopeptidase
C6ORF48 chromosome 6 open reading frame 48
CCNA2 cyclin A2
CCND1 cyclin D1
CCNF cyclin F
CDC25B cell division cycle 25B
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CENPA centromere protein A
CENPE centromere protein E, 312kDa
CPVL carboxypeptidase, vitellogenic-like
CTSH cathepsin H
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL5 chemokine (C-X-C motif) ligand 5
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DUSP4 dual specificity phosphatase 4
EREG epiregulin
HOXA10 homeobox A10
IL1R2 interleukin 1 receptor, type II
KIF20A kinesin family member 20A
LBR lamin B receptor
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
NR2F2 nuclear receptor subfamily 2, group F, member 2
PLK1 polo-like kinase 1
PRC1 protein regulator of cytokinesis 1
PRSS3 protease, serine, 3
RET ret proto-oncogene
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
TFF1 trefoil factor 1
TNC tenascin C
TSPAN8 tetraspanin 8
UBE2C ubiquitin-conjugating enzyme E2C