BRD-A47633927_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-A47633927_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALOX15B arachidonate 15-lipoxygenase, type B
ANO1 anoctamin 1, calcium activated chloride channel
ANPEP alanyl (membrane) aminopeptidase
C1S complement component 1, s subcomponent
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL3A1 collagen, type III, alpha 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
DSP desmoplakin
FABP7 fatty acid binding protein 7, brain
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
H1F0 H1 histone family, member 0
HOXC6 homeobox C6
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
INSR insulin receptor
IQCG IQ motif containing G
ISLR immunoglobulin superfamily containing leucine-rich repeat
KRT14 keratin 14, type I
MAMLD1 mastermind-like domain containing 1
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
NAAA N-acylethanolamine acid amidase
NDRG2 NDRG family member 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NPY1R neuropeptide Y receptor Y1
OPN3 opsin 3
OXTR oxytocin receptor
PEBP1 phosphatidylethanolamine binding protein 1
PIP prolactin-induced protein
POSTN periostin, osteoblast specific factor
RBM3 RNA binding motif (RNP1, RRM) protein 3
RPL37A ribosomal protein L37a
S100A7 S100 calcium binding protein A7
SCGB2A2 secretoglobin, family 2A, member 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC31A2 solute carrier family 31 (copper transporter), member 2
STC2 stanniocalcin 2
STEAP1 six transmembrane epithelial antigen of the prostate 1
TBC1D31 TBC1 domain family, member 31
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TNS1 tensin 1
TSPYL5 TSPY-like 5
WASF3 WAS protein family, member 3
ZBTB16 zinc finger and BTB domain containing 16

decreased expression

Symbol Name
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMIGO2 adhesion molecule with Ig-like domain 2
ATP9A ATPase, class II, type 9A
BLNK B-cell linker
CADM1 cell adhesion molecule 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CD9 CD9 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CPA3 carboxypeptidase A3 (mast cell)
CRISP3 cysteine-rich secretory protein 3
CTNND1 catenin (cadherin-associated protein), delta 1
CXADR coxsackie virus and adenovirus receptor
CYBB cytochrome b-245, beta polypeptide
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ERAP1 endoplasmic reticulum aminopeptidase 1
FBN2 fibrillin 2
FSD1 fibronectin type III and SPRY domain containing 1
HPSE heparanase
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGL immunoglobulin lambda locus
LPAR6 lysophosphatidic acid receptor 6
MFSD10 major facilitator superfamily domain containing 10
NOTCH1 notch 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SPINK1 serine peptidase inhibitor, Kazal type 1
TFF2 trefoil factor 2
TLR4 toll-like receptor 4
TNNT1 troponin T type 1 (skeletal, slow)
TXNDC9 thioredoxin domain containing 9
ZNF586 zinc finger protein 586