BRD-A47513740_calyculin A_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-A47513740_calyculin A_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACLY ATP citrate lyase
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AKAP8L A kinase (PRKA) anchor protein 8-like
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKRD10 ankyrin repeat domain 10
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
BEX1 brain expressed, X-linked 1
BRD8 bromodomain containing 8
CST3 cystatin C
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EGR1 early growth response 1
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB2 erb-b2 receptor tyrosine kinase 2
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXO4 forkhead box O4
GADD45B growth arrest and DNA-damage-inducible, beta
GATA2 GATA binding protein 2
GOLGA8A golgin A8 family, member A
GRAMD3 GRAM domain containing 3
HEXIM1 hexamethylene bis-acetamide inducible 1
HOOK2 hook microtubule-tethering protein 2
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IP6K2 inositol hexakisphosphate kinase 2
JUN jun proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
MFSD10 major facilitator superfamily domain containing 10
NNMT nicotinamide N-methyltransferase
NUP62 nucleoporin 62kDa
OXTR oxytocin receptor
PAN2 PAN2 poly(A) specific ribonuclease subunit
PFKP phosphofructokinase, platelet
PILRB paired immunoglobin-like type 2 receptor beta
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
RBM6 RNA binding motif protein 6
SFN stratifin
SFTPA2 surfactant protein A2
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1)
SOX4 SRY (sex determining region Y)-box 4
SRSF6 serine/arginine-rich splicing factor 6
SRSF7 serine/arginine-rich splicing factor 7
USP48 ubiquitin specific peptidase 48
WDR6 WD repeat domain 6
WSB1 WD repeat and SOCS box containing 1
ZMYND8 zinc finger, MYND-type containing 8

decreased expression

Symbol Name
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ARL4C ADP-ribosylation factor-like 4C
AUTS2 autism susceptibility candidate 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BAD BCL2-associated agonist of cell death
BEX4 brain expressed, X-linked 4
CD52 CD52 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLEC2B C-type lectin domain family 2, member B
CLEC7A C-type lectin domain family 7, member A
CTSS cathepsin S
FXYD6 FXYD domain containing ion transport regulator 6
GNLY granulysin
IFNGR1 interferon gamma receptor 1
IL13RA2 interleukin 13 receptor, alpha 2
IL1R2 interleukin 1 receptor, type II
IL32 interleukin 32
LUM lumican
MMP9 matrix metallopeptidase 9
MOXD1 monooxygenase, DBH-like 1
NQO2 NAD(P)H dehydrogenase, quinone 2
RAD21 RAD21 homolog (S. pombe)
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGCC regulator of cell cycle
SHB Src homology 2 domain containing adaptor protein B
TCF21 transcription factor 21
TOPBP1 topoisomerase (DNA) II binding protein 1
ZFPM2 zinc finger protein, FOG family member 2