BRD-A47513740_calyculin A_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

91 genes differentially expressed following the BRD-A47513740_calyculin A_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADCY7 adenylate cyclase 7
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ASS1 argininosuccinate synthase 1
C8ORF4 chromosome 8 open reading frame 4
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CRISP3 cysteine-rich secretory protein 3
CSAD cysteine sulfinic acid decarboxylase
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
DDAH1 dimethylarginine dimethylaminohydrolase 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP1 dual specificity phosphatase 1
EFHD1 EF-hand domain family, member D1
EIF1 eukaryotic translation initiation factor 1
EREG epiregulin
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45B growth arrest and DNA-damage-inducible, beta
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GOLGA8H golgin A8 family, member H
GREM1 gremlin 1, DAN family BMP antagonist
GRIA2 glutamate receptor, ionotropic, AMPA 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IGFBP5 insulin-like growth factor binding protein 5
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL1R1 interleukin 1 receptor, type I
IRS2 insulin receptor substrate 2
KLF4 Kruppel-like factor 4 (gut)
KRT19 keratin 19, type I
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LIMCH1 LIM and calponin homology domains 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAP7 microtubule-associated protein 7
MB myoglobin
MFAP5 microfibrillar associated protein 5
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
RABGAP1L RAB GTPase activating protein 1-like
RBM6 RNA binding motif protein 6
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFRP4 secreted frizzled-related protein 4
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SNAI2 snail family zinc finger 2
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SULF1 sulfatase 1
TFPI2 tissue factor pathway inhibitor 2
THBD thrombomodulin
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TRAF5 TNF receptor-associated factor 5
VEGFA vascular endothelial growth factor A
XIST X inactive specific transcript (non-protein coding)
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BAD BCL2-associated agonist of cell death
BST2 bone marrow stromal cell antigen 2
CD151 CD151 molecule (Raph blood group)
CD320 CD320 molecule
CD59 CD59 molecule, complement regulatory protein
CKAP4 cytoskeleton-associated protein 4
COCH cochlin
CYFIP2 cytoplasmic FMR1 interacting protein 2
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF5A eukaryotic translation initiation factor 5A
FAM129A family with sequence similarity 129, member A
FBLN1 fibulin 1
ISG20 interferon stimulated exonuclease gene 20kDa
MSH6 mutS homolog 6
NES nestin
PCCB propionyl CoA carboxylase, beta polypeptide
PHB prohibitin
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
PRMT1 protein arginine methyltransferase 1
PRMT5 protein arginine methyltransferase 5
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PTN pleiotrophin
RPS4Y1 ribosomal protein S4, Y-linked 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPTBN1 spectrin, beta, non-erythrocytic 1
SRPX sushi-repeat containing protein, X-linked
TARS threonyl-tRNA synthetase
TLK2 tousled-like kinase 2
TUBB2A tubulin, beta 2A class IIa
UGCG UDP-glucose ceramide glucosyltransferase