BRD-A46186775_HYDROCORTISONE PHOSPHATE TRIETHYLAMINE_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

161 genes differentially expressed following the BRD-A46186775_HYDROCORTISONE PHOSPHATE TRIETHYLAMINE_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
AIM1 absent in melanoma 1
AKAP12 A kinase (PRKA) anchor protein 12
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
C10ORF10 chromosome 10 open reading frame 10
C1QA complement component 1, q subcomponent, A chain
C3 complement component 3
C5AR1 complement component 5a receptor 1
CA2 carbonic anhydrase II
CD163 CD163 molecule
CD24 CD24 molecule
CD47 CD47 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CELF2 CUGBP, Elav-like family member 2
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLIC5 chloride intracellular channel 5
CREG1 cellular repressor of E1A-stimulated genes 1
CXCL2 chemokine (C-X-C motif) ligand 2
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DEFB1 defensin, beta 1
DLD dihydrolipoamide dehydrogenase
EGFR epidermal growth factor receptor
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
F13A1 coagulation factor XIII, A1 polypeptide
FAM107A family with sequence similarity 107, member A
FCGBP Fc fragment of IgG binding protein
FKBP5 FK506 binding protein 5
FPR1 formyl peptide receptor 1
FZD6 frizzled class receptor 6
GADD45B growth arrest and DNA-damage-inducible, beta
GLUL glutamate-ammonia ligase
GPX3 glutathione peroxidase 3
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HP haptoglobin
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IGL immunoglobulin lambda locus
JAG2 jagged 2
JUNB jun B proto-oncogene
KLF9 Kruppel-like factor 9
KRT5 keratin 5, type II
LAMA3 laminin, alpha 3
LOX lysyl oxidase
MAOA monoamine oxidase A
MECOM MDS1 and EVI1 complex locus
MT1M metallothionein 1M
MT1X metallothionein 1X
MTSS1 metastasis suppressor 1
MXI1 MAX interactor 1, dimerization protein
NAMPT nicotinamide phosphoribosyltransferase
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOTCH1 notch 1
NPTX2 neuronal pentraxin II
PDZD2 PDZ domain containing 2
PER1 period circadian clock 1
PFKL phosphofructokinase, liver
PFN2 profilin 2
PLBD1 phospholipase B domain containing 1
PPL periplakin
PRR15L proline rich 15-like
PTPRO protein tyrosine phosphatase, receptor type, O
RAB25 RAB25, member RAS oncogene family
RGS2 regulator of G-protein signaling 2
RHOB ras homolog family member B
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIK1 salt-inducible kinase 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLPI secretory leukocyte peptidase inhibitor
SRGN serglycin
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
THAP11 THAP domain containing 11
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
VSIG4 V-set and immunoglobulin domain containing 4
ZBTB16 zinc finger and BTB domain containing 16
ZFP36 ZFP36 ring finger protein
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
AGTR1 angiotensin II receptor, type 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AMIGO2 adhesion molecule with Ig-like domain 2
ARL4C ADP-ribosylation factor-like 4C
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
AXL AXL receptor tyrosine kinase
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CCL19 chemokine (C-C motif) ligand 19
CCL2 chemokine (C-C motif) ligand 2
CD58 CD58 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CIAPIN1 cytokine induced apoptosis inhibitor 1
CST1 cystatin SN
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CYR61 cysteine-rich, angiogenic inducer, 61
DACH1 dachshund family transcription factor 1
DLX2 distal-less homeobox 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DST dystonin
DUSP10 dual specificity phosphatase 10
DUSP4 dual specificity phosphatase 4
EGR2 early growth response 2
EPHA3 EPH receptor A3
FAM129A family with sequence similarity 129, member A
FAM46A family with sequence similarity 46, member A
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGF13 fibroblast growth factor 13
FOSL1 FOS-like antigen 1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GATA6 GATA binding protein 6
IER3 immediate early response 3
JUN jun proto-oncogene
KDM3A lysine (K)-specific demethylase 3A
KYNU kynureninase
LGALS1 lectin, galactoside-binding, soluble, 1
LMCD1 LIM and cysteine-rich domains 1
LPXN leupaxin
LYN LYN proto-oncogene, Src family tyrosine kinase
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAP7 microtubule-associated protein 7
MARCKS myristoylated alanine-rich protein kinase C substrate
MCOLN1 mucolipin 1
NREP neuronal regeneration related protein
NTS neurotensin
PALLD palladin, cytoskeletal associated protein
PEA15 phosphoprotein enriched in astrocytes 15
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIP prolactin-induced protein
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PPIF peptidylprolyl isomerase F
PTN pleiotrophin
RBP1 retinol binding protein 1, cellular
SCGB2A2 secretoglobin, family 2A, member 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
SMS spermine synthase
SOX2 SRY (sex determining region Y)-box 2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPRY2 sprouty homolog 2 (Drosophila)
TBX3 T-box 3
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TGFBI transforming growth factor, beta-induced, 68kDa
TLE4 transducin-like enhancer of split 4
TMEM47 transmembrane protein 47
TNC tenascin C
TOX3 TOX high mobility group box family member 3
VCL vinculin
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZMIZ1 zinc finger, MIZ-type containing 1