BRD-A46186775_HYDROCORTISONE PHOSPHATE TRIETHYLAMINE_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-A46186775_HYDROCORTISONE PHOSPHATE TRIETHYLAMINE_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL1 acyl-CoA synthetase long-chain family member 1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALOX5 arachidonate 5-lipoxygenase
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCND1 cyclin D1
CD24 CD24 molecule
CD52 CD52 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CES1 carboxylesterase 1
CPM carboxypeptidase M
CRIP1 cysteine-rich protein 1 (intestinal)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DUSP1 dual specificity phosphatase 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFHD1 EF-hand domain family, member D1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FAIM Fas apoptotic inhibitory molecule
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FKBP5 FK506 binding protein 5
FOS FBJ murine osteosarcoma viral oncogene homolog
FRY furry homolog (Drosophila)
GADD45B growth arrest and DNA-damage-inducible, beta
GATA2 GATA binding protein 2
IL1R1 interleukin 1 receptor, type I
INHBA inhibin, beta A
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KLF2 Kruppel-like factor 2
LAMB1 laminin, beta 1
LTF lactotransferrin
MET MET proto-oncogene, receptor tyrosine kinase
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NUPR1 nuclear protein, transcriptional regulator, 1
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RTN3 reticulon 3
S100A2 S100 calcium binding protein A2
SCGB2A2 secretoglobin, family 2A, member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TNS1 tensin 1
TPP1 tripeptidyl peptidase I
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
VCAN versican
ZBTB16 zinc finger and BTB domain containing 16
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
AMPH amphiphysin
BZW2 basic leucine zipper and W2 domains 2
CBR3 carbonyl reductase 3
CCL2 chemokine (C-C motif) ligand 2
CD58 CD58 molecule
CLDN10 claudin 10
CLTB clathrin, light chain B
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL8 chemokine (C-X-C motif) ligand 8
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
FOSL1 FOS-like antigen 1
HSPA8 heat shock 70kDa protein 8
IFRD2 interferon-related developmental regulator 2
MYOF myoferlin
PFKP phosphofructokinase, platelet
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLK2 polo-like kinase 2
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC35F2 solute carrier family 35, member F2
SMAD3 SMAD family member 3
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
TSPAN8 tetraspanin 8
TUBB2A tubulin, beta 2A class IIa