BRD-A45540146_KI20227_HT29_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

86 genes differentially expressed following the BRD-A45540146_KI20227_HT29_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
BCHE butyrylcholinesterase
C3ORF14 chromosome 3 open reading frame 14
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
COMP cartilage oligomeric matrix protein
CTSG cathepsin G
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GCH1 GTP cyclohydrolase 1
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
HBB hemoglobin, beta
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ISG15 ISG15 ubiquitin-like modifier
KRT14 keratin 14, type I
KRT81 keratin 81, type II
LPL lipoprotein lipase
LYN LYN proto-oncogene, Src family tyrosine kinase
MARCKS myristoylated alanine-rich protein kinase C substrate
MATN2 matrilin 2
MFAP5 microfibrillar associated protein 5
MT1E metallothionein 1E
MX1 MX dynamin-like GTPase 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NSG1 neuron specific gene family member 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PBX3 pre-B-cell leukemia homeobox 3
PEG10 paternally expressed 10
PEG3 paternally expressed 3
PIP prolactin-induced protein
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SF1 splicing factor 1
TARP TCR gamma alternate reading frame protein
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VCAM1 vascular cell adhesion molecule 1
WT1 Wilms tumor 1

decreased expression

Symbol Name
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AMIGO2 adhesion molecule with Ig-like domain 2
AREG amphiregulin
DKK3 dickkopf WNT signaling pathway inhibitor 3
DRAM1 DNA-damage regulated autophagy modulator 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EMP1 epithelial membrane protein 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPAS1 endothelial PAS domain protein 1
FBLN1 fibulin 1
FKBP11 FK506 binding protein 11, 19 kDa
GLUL glutamate-ammonia ligase
GPRC5A G protein-coupled receptor, class C, group 5, member A
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
IL1R1 interleukin 1 receptor, type I
KIF5B kinesin family member 5B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MET MET proto-oncogene, receptor tyrosine kinase
MMP12 matrix metallopeptidase 12
MYH11 myosin, heavy chain 11, smooth muscle
MYOF myoferlin
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
PDLIM5 PDZ and LIM domain 5
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLIN3 perilipin 3
PODXL podocalyxin-like
PPAP2B phosphatidic acid phosphatase type 2B
PRSS21 protease, serine, 21 (testisin)
RGCC regulator of cell cycle
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SFRP1 secreted frizzled-related protein 1
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
ST18 suppression of tumorigenicity 18, zinc finger
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STXBP2 syntaxin binding protein 2
TGM2 transglutaminase 2
TMPRSS2 transmembrane protease, serine 2
TPM2 tropomyosin 2 (beta)
TPPP3 tubulin polymerization-promoting protein family member 3
UBXN7 UBX domain protein 7
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1